Description

5-Bromo-6-chloropyridin-3-amine (CAS No. 130284-53-6) is a high-purity halogenated pyridine derivative with the molecular formula C₅H₄BrClN₂. This compound is a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals. With a molecular weight of 207.46 g/mol, it features both bromo and chloro substituents on a pyridine ring, offering unique reactivity for cross-coupling reactions, nucleophilic substitutions, and other transformations. Its high stability and well-characterized properties make it ideal for research applications in medicinal chemistry and material science. Available in >97% purity, this product is rigorously tested by HPLC, NMR, and mass spectrometry to ensure quality and consistency for demanding laboratory use.

Properties

• CAS Number: 130284-53-6
• Complexity: 101
• IUPAC Name: 5-bromo-6-chloro-pyridin-3-amine
• InChI: InChI=1S/C5H4BrClN2/c6-4-1-3(8)2-9-5(4)7/h1-2H,8H2
• InChI Key: ISKBXMMELYRESC-UHFFFAOYSA-N
• Exact Mass: 205.92464
• Molecular Formula: C5H4BrClN2
• Molecular Weight: 207.45
• SMILES: C1=C(C=NC(=C1Br)Cl)N
• Topological: 38.9
• Monoisotopic Mass: 205.92464
• Synonyms: 130284-53-6, 5-bromo-6-chloropyridin-3-amine, 5-BROMO-6-CHLORO-3-PYRIDINAMINE, DTXSID80562010, DTXCID70512786, 639-377-7, 5-Amino-3-bromo-2-chloropyridine, 2-Chloro-3-bromo-5-aminopyridine, 3-PYRIDINAMINE, 5-BROMO-6-CHLORO-, MFCD03840433, 3-AMINO-5-BROMO-6-CHLOROPYRIDINE, EN300-112006, SCHEMBL2487120, 5-bromo-6-chloro-3-pyridylamine, ISKBXMMELYRESC-UHFFFAOYSA-N, BDBM625982, BCP23342, BBL102996, SBB070447, STL556805, AKOS005255537, AC-5436, CS-W020112, PS-3326, 5-Amino-3-bromo-2-chloropyridine, 97%, SY019775, DB-024934, A2539

5-Bromo-6-chloropyridin-3-amine is widely used as a key building block in the synthesis of bioactive molecules, including drug candidates and agrochemicals. Its reactive halogen groups enable participation in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions. Researchers also utilize it in the development of heterocyclic compounds for optoelectronic materials. Suitable for small-scale R&D and bulk manufacturing under controlled conditions.

Safety and Hazards

GHS Hazard Statements

• H301 (90.9%): Toxic if swallowed [Danger Acute toxicity, oral]
• H315 (11.4%): Causes skin irritation [Warning Skin corrosion/irritation]
• H318 (93.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P270, P280, P301+P316, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (90.9%)
• Skin Irrit. 2 (11.4%)
• Eye Dam. 1 (93.2%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.