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Atomfair 3-(tetrahydro-2H-pyran-2-yloxy)phenylboronic acid C11H15BO4 CAS 1287777-05-2

3-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid (CAS: 1287777-05-2) is a high-purity boronic acid derivative with the molecular formula C11H15BO4. This compound, also known by its IUPAC name [3-(oxan-2-yloxy)phenyl]boronic acid , is a valuable synthetic intermediate in organic and medicinal chemistry. The tetrahydropyranyl (THP) protecting group enhances its stability and reactivity, making it ideal for Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern C-C bond formation. Our product is rigorously tested to ensure >95% purity (HPLC) and is supplied as a white to off-white crystalline powder under inert conditions to maintain integrity. Suitable for researchers in pharmaceuticals, agrochemicals, and materials science, this boronic acid derivative is…

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Description

3-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid (CAS: 1287777-05-2) is a high-purity boronic acid derivative with the molecular formula C11H15BO4. This compound, also known by its IUPAC name [3-(oxan-2-yloxy)phenyl]boronic acid, is a valuable synthetic intermediate in organic and medicinal chemistry. The tetrahydropyranyl (THP) protecting group enhances its stability and reactivity, making it ideal for Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern C-C bond formation. Our product is rigorously tested to ensure >95% purity (HPLC) and is supplied as a white to off-white crystalline powder under inert conditions to maintain integrity. Suitable for researchers in pharmaceuticals, agrochemicals, and materials science, this boronic acid derivative is packaged in amber glass vials with moisture-resistant seals to ensure long-term stability. Store at 2-8°C in a dry environment.

Properties

  • CAS Number: 1287777-05-2
  • Complexity: 212
  • IUPAC Name: (3-tetrahydropyran-2-yloxyphenyl)boronic acid
  • InChI: InChI=1S/C11H15BO4/c13-12(14)9-4-3-5-10(8-9)16-11-6-1-2-7-15-11/h3-5,8,11,13-14H,1-2,6-7H2
  • InChI Key: GPYBHNZRMWCEAW-UHFFFAOYSA-N
  • Exact Mass: 222.1063391
  • Molecular Formula: C11H15BO4
  • Molecular Weight: 222.05
  • SMILES: B(C1=CC(=CC=C1)OC2CCCCO2)(O)O
  • Topological: 58.9
  • Monoisotopic Mass: 222.1063391
  • Synonyms: 1287777-05-2, 3-(tetrahydro-2H-pyran-2-yloxy)phenylboronic acid, 3-(Tetrahydropyran-2-yloxy)phenylboronic acid, (3-((Tetrahydro-2H-pyran-2-yl)oxy)phenyl)boronic acid, 3-[(2-Tetrahydropyranyl)oxy]phenylboronic Acid, [3-(oxan-2-yloxy)phenyl]boronic acid, Boronic acid, B-[3-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-, MFCD03425971, (3-((Tetrahydro-2H-pyran-2-yl)oxy)phenyl)boronicacid, DTXSID10676795, AC3662, AKOS015918356, AB14733, {3-[(Oxan-2-yl)oxy]phenyl}boronic acid, AS-11410, SY104690, DB-228407, CS-0155243, (3-Tetrahydropyran-2-yloxyphenyl)boronic acid, 3-[(2-Tetrahydropyranyl)oxy]phenylboronicAcid

Application

3-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid is widely used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds, which are prevalent in drug discovery and materials science. Its THP-protected hydroxyl group offers improved solubility and handling compared to unprotected analogs. This compound is particularly valuable in the development of pharmaceutical candidates, agrochemicals, and functionalized polymers. Researchers also employ it in the synthesis of advanced organic frameworks and ligands for catalysis.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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Certain molecules may be protected by active patents or regulatory restrictions.

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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