Description
2-Fluoro-6-hydroxyphenylboronic acid (CAS No. 1256345-60-4) is a high-purity boronic acid derivative designed for advanced research and pharmaceutical applications. With the molecular formula C6H6BFO3, this compound is a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its unique fluorinated and hydroxylated aromatic structure makes it invaluable for constructing complex molecules in medicinal chemistry and material science. The product is rigorously tested for quality, ensuring consistent performance in sensitive applications. Available in various quantities, it is packaged under inert conditions to maintain stability and purity.
Properties
- CAS Number: 1256345-60-4
- Complexity: 133
- IUPAC Name: (2-fluoro-6-hydroxy-phenyl)boronic acid
- InChI: InChI=1S/C6H6BFO3/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,9-11H
- InChI Key: FPXQHZPCFRQWCP-UHFFFAOYSA-N
- Exact Mass: 156.0394024
- Molecular Formula: C6H6BFO3
- Molecular Weight: 155.92
- SMILES: B(C1=C(C=CC=C1F)O)(O)O
- Topological: 60.7
- Monoisotopic Mass: 156.0394024
- Synonyms: 2-FLUORO-6-HYDROXYPHENYLBORONIC ACID, 815-950-9, 1256345-60-4, (2-Fluoro-6-hydroxyphenyl)boronic acid, Boronic acid, B-(2-fluoro-6-hydroxyphenyl)-, MFCD17214242, (2-Fluoro-6-hydroxyphenyl)boronicacid, B-(2-Fluoro-6-hydroxyphenyl)boronic Acid;, SCHEMBL15475873, DTXSID80681533, FPXQHZPCFRQWCP-UHFFFAOYSA-N, ZB0260, AKOS015853280, DS-17595, SY226646, DB-347041, CS-0043300, W13758, 2-Fluoro-6-hydroxyphenylboronic acid(contains varying amounts of Anhydride)
2-Fluoro-6-hydroxyphenylboronic acid is widely used in pharmaceutical research as a key intermediate for synthesizing bioactive compounds. Its boronic acid group enables efficient cross-coupling reactions, while the fluorine and hydroxyl substituents enhance binding affinity in drug design. This compound is also employed in materials science for developing fluorescent probes and sensors. Researchers utilize it in the preparation of advanced polymers and ligands for catalysis.
Safety and Hazards
GHS Hazard Statements
- H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (50%)
- Eye Irrit. 2 (50%)
- STOT SE 3 (50%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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