Description
(R)-alpha-Methyl-4-Iodophenylalaine (CAS: 1241679-14-0) is a high-purity, chiral amino acid derivative with the molecular formula C10H12INO2. Its IUPAC name is (2R)-2-amino-3-(4-iodophenyl)-2-methylpropanoic acid, featuring a stereogenic center at the alpha-carbon, making it valuable for asymmetric synthesis and pharmaceutical research. This compound is characterized by its iodinated phenyl ring and methyl-substituted alanine backbone, offering unique reactivity in peptide modifications and radiolabeling applications. Provided as a white to off-white crystalline powder, it is rigorously tested for identity, purity, and chiral integrity via HPLC, NMR, and mass spectrometry. Suitable for use in medicinal chemistry, radiopharmaceuticals, and as a building block in organic synthesis. Store under inert conditions at -20°C to ensure long-term stability.
Properties
- CAS Number: 1241679-14-0
- Complexity: 214
- IUPAC Name: (2R)-2-amino-3-(4-iodophenyl)-2-methyl-propanoic acid
- InChI: InChI=1S/C10H12INO2/c1-10(12,9(13)14)6-7-2-4-8(11)5-3-7/h2-5H,6,12H2,1H3,(H,13,14)/t10-/m1/s1
- InChI Key: YNCJAZPOXKKAMD-SNVBAGLBSA-N
- Exact Mass: 304.99128
- Molecular Formula: C10H12INO2
- Molecular Weight: 305.11
- SMILES: C[C@@](CC1=CC=C(C=C1)I)(C(=O)O)N
- Topological: 63.3
- Monoisotopic Mass: 304.99128
- Synonyms: 213203-06-6, (R)-alpha-Methyl-4-Iodophenylalaine, (2R)-2-amino-3-(4-iodophenyl)-2-methylpropanoic acid, (R)-2-Amino-3-(4-iodophenyl)-2-methylpropanoic acid, 1241679-14-0, 4-Iodo–methyl-D-phenylalanine, 4-iodo-?-methyl-d-phenylalanine, 4-Iodo-alpha-methyl-D-phenylalanine, AKOS030213017
Application
(R)-alpha-Methyl-4-Iodophenylalaine is widely used in pharmaceutical research as a chiral precursor for the synthesis of bioactive molecules and peptidomimetics. Its iodinated aromatic ring makes it a valuable intermediate for radiolabeling applications in PET imaging and tracer studies. Researchers also employ this compound in the development of enzyme inhibitors and receptor ligands due to its structural similarity to natural amino acids.
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