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Atomfair 3-Fluorocyclobutanamine C4H8FN CAS 1234616-60-4

3-Fluorocyclobutanamine (CAS: 1234616-60-4) is a high-purity fluorinated cyclobutanamine derivative with the molecular formula C4H8FN . This compound, also known as 3-fluorocyclobutan-1-amine (IUPAC name), is a valuable building block in medicinal chemistry and pharmaceutical research. Available in both cis and trans isomeric forms, it is characterized by its cyclobutane backbone with a fluorine substituent at the 3-position and an amine group at the 1-position. The fluorine atom enhances metabolic stability and bioavailability, making it ideal for drug discovery applications. Our product is synthesized under strict quality control, ensuring ≥95% purity (HPLC) and is supplied in sealed containers under inert gas to…

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Description

3-Fluorocyclobutanamine (CAS: 1234616-60-4) is a high-purity fluorinated cyclobutanamine derivative with the molecular formula C4H8FN. This compound, also known as 3-fluorocyclobutan-1-amine (IUPAC name), is a valuable building block in medicinal chemistry and pharmaceutical research. Available in both cis and trans isomeric forms, it is characterized by its cyclobutane backbone with a fluorine substituent at the 3-position and an amine group at the 1-position. The fluorine atom enhances metabolic stability and bioavailability, making it ideal for drug discovery applications. Our product is synthesized under strict quality control, ensuring ≥95% purity (HPLC) and is supplied in sealed containers under inert gas to prevent degradation. Suitable for use in nucleophilic substitutions, cross-coupling reactions, and as a precursor for bioactive molecules.

Properties

  • CAS Number: 1234616-60-4
  • Complexity: 49.5
  • IUPAC Name: 3-fluorocyclobutanamine
  • InChI: InChI=1S/C4H8FN/c5-3-1-4(6)2-3/h3-4H,1-2,6H2
  • InChI Key: APCSZMINSACNSQ-UHFFFAOYSA-N
  • Exact Mass: 89.064077422
  • Molecular Formula: C4H8FN
  • Molecular Weight: 89.11
  • SMILES: C1C(CC1F)N
  • Topological: 26
  • Monoisotopic Mass: 89.064077422
  • Synonyms: 3-FLUOROCYCLOBUTANAMINE, cis-3-Fluorocyclobutanamine, trans-3-Fluorocyclobutanamine, 1234616-60-4, 3-fluorocyclobutan-1-amine, 1260670-33-4, 1260670-54-9, 3-FLUORO-CYCLOBUTYLAMINE, Cyclobutanamine, 3-fluoro-, trans-, 5X99FNC2UU, C5P3VQT3J9, 3-Fluorocyclobutanamine, cis-, 3-Fluorocyclobutanamine, trans-, Cyclobutanamine, 3-fluoro-, cis-, 3-Fluorocyclobutan-1-amine HCl, Cis-3-Fluoro-cyclobutylamine, Trans-3-Fluoro-cyclobutylamine, MFCD18249868, MFCD18249869, UNII-5X99FNC2UU, UNII-C5P3VQT3J9, SCHEMBL10188243, SCHEMBL16908304, SCHEMBL21962863, DTXSID50705432, DTXSID101309997, DTXSID601297210, (1r,3r)-3-fluorocyclobutan-1-amine, (1s,3s)-3-fluorocyclobutan-1-amine, AKOS015949255, AKOS025212007, AKOS025212112, PB22829, PB35807, PB37634, SB20572, SB20574, SY310838, SY310839, DB-348221, CS-0055188, CS-0057520, CS-0057521, EN300-82802, EN300-133411, EN300-133412, P12018

Application

3-Fluorocyclobutanamine is widely used in pharmaceutical research as a key intermediate for designing novel bioactive compounds, particularly in CNS-targeting drugs. Its fluorinated cyclobutane structure contributes to improved metabolic stability and binding affinity in drug candidates. Researchers utilize it in the synthesis of protease inhibitors, receptor modulators, and PET radiotracer development. The compound’s rigid scaffold also aids in conformational restriction studies for peptide mimetics.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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Certain molecules may be protected by active patents or regulatory restrictions.

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  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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