Atomfair N-methoxy-1-(2,4,6-trichlorophenyl)propan-2-amine C10H12Cl3NO CAS 1228284-78-3

Description

N-methoxy-1-(2,4,6-trichlorophenyl)propan-2-amine (CAS No. 1228284-78-3) is a high-purity specialty chemical with the molecular formula C₁₀H₁₂Cl₃NO. This compound features a trichlorophenyl backbone coupled with a propan-2-amine moiety modified by a methoxy group, making it a valuable intermediate in organic synthesis and pharmaceutical research. Its structural complexity and halogen-rich composition lend it to applications in cross-coupling reactions, ligand design, and medicinal chemistry studies. Available in rigorously controlled batches, this product is ideal for researchers requiring precise and reproducible results. Each shipment includes comprehensive analytical data (HPLC, NMR, MS) to ensure quality and consistency for your experiments.

Properties

• CAS Number: 1228284-78-3
• Complexity: 182
• IUPAC Name: N-methoxy-1-(2,4,6-trichlorophenyl)propan-2-amine
• InChI: InChI=1S/C10H12Cl3NO/c1-6(14-15-2)3-8-9(12)4-7(11)5-10(8)13/h4-6,14H,3H2,1-2H3
• InChI Key: YEYSNJKFDGOAAP-UHFFFAOYSA-N
• Exact Mass: 266.998447
• Molecular Formula: C10H12Cl3NO
• Molecular Weight: 268.6
• SMILES: CC(CC1=C(C=C(C=C1Cl)Cl)Cl)NOC
• Topological: 21.3
• Monoisotopic Mass: 266.998447
• Synonyms: 1228284-78-3, N-methoxy-1-(2,4,6-trichlorophenyl)propan-2-amine, 941-634-6, O-METHYL-N-(1-(2,4,6-TRICHLOROPHENYL)PROPAN-2-YL)HYDROXYLAMINE, 2,4,6-Trichloro-N-methoxy-a-methylbenzeneethanamine, SCHEMBL2366778, YEYSNJKFDGOAAP-UHFFFAOYSA-N, O-Methyl-N-[1-methyl-2-(2,4,6-trichloro-phenyl)-ethyl]-hydroxylamine, E72425

Application

N-methoxy-1-(2,4,6-trichlorophenyl)propan-2-amine serves as a versatile building block in synthetic organic chemistry, particularly in the development of novel pharmacophores. Its trichlorophenyl group enhances electrophilic reactivity, facilitating use in Suzuki-Miyaura or Buchwald-Hartwig couplings. Researchers also employ it as a precursor for bioactive molecule synthesis, leveraging its amine and methoxy functional groups. The compound’s stability under acidic conditions makes it suitable for heterocycle formation and catalyst design.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
• H373 (93.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
• H411 (93.3%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P260, P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P319, P321, P330, P332+P317, P333+P317, P362+P364, P391, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Skin Sens. 1B (100%)
• STOT RE 2 (93.3%)
• Aquatic Chronic 2 (93.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.