Description

5-Fluoropyridine-2-carboxylic Acid (CAS No. 107504-08-5) is a high-purity fluorinated heterocyclic compound widely utilized in pharmaceutical research, agrochemical development, and material science applications. With the molecular formula C₆H₄FNO₂, this white to off-white crystalline powder exhibits excellent stability and solubility in common organic solvents, making it an essential building block for synthesizing bioactive molecules and advanced intermediates. Our product undergoes rigorous QC testing (HPLC, NMR) to ensure ≥98% purity, meeting the stringent requirements of industrial and academic researchers. Available in scalable quantities (mg to kg), it is supplied with comprehensive analytical data, including MSDS and COA.

Properties

• CAS Number: 107504-08-5
• Complexity: 140
• IUPAC Name: 5-fluoropyridine-2-carboxylic acid
• InChI: InChI=1S/C6H4FNO2/c7-4-1-2-5(6(9)10)8-3-4/h1-3H,(H,9,10)
• InChI Key: JTKFIIQGMVKDNZ-UHFFFAOYSA-N
• Exact Mass: 141.02260653
• Molecular Formula: C6H4FNO2
• Molecular Weight: 141.10
• SMILES: C1=CC(=NC=C1F)C(=O)O
• Topological: 50.2
• Monoisotopic Mass: 141.02260653
• Synonyms: 107504-08-5, 5-fluoropyridine-2-carboxylic Acid, DTXSID80376533, DTXCID40327561, 675-772-0, 5-Fluoro-2-picolinic acid, 5-Fluoropicolinic acid, 5-FLUORO-2-PYRIDINECARBOXYLIC ACID, MFCD04114196, 2-PYRIDINECARBOXYLIC ACID, 5-FLUORO-, 5-Fluoro-pyridine-2-carboxylic acid, SCHEMBL110129, 5-fluoropyridin-2-carboxylic acid, JTKFIIQGMVKDNZ-UHFFFAOYSA-N, 5-fluor-pyridine-2-carboxylic acid, BCP26704, 3-fluoro-pyridine-6-carboxylic acid, 5-Fluoro-2-pyridine carboxylic acid, BBL101179, SBB065401, STL554975, AKOS005063379, AB17969, CS-W003161, PS-9026, SY008116, DB-001314, F0838, EN300-42378, 5-Fluoropyridine-2-carboxylic acid, AldrichCPR, Z425834578

5-Fluoropyridine-2-carboxylic Acid serves as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly kinase inhibitors and antiviral agents. Its pyridine core and carboxylic acid functionality enable versatile derivatization for drug discovery programs. Researchers also employ it in ligand design for catalysis and as a precursor for agrochemical active ingredients. The fluorine substitution enhances metabolic stability in target molecules.

Safety and Hazards

GHS Hazard Statements

• H315 (90%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (90%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (70%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (90%)
• Eye Irrit. 2A (90%)
• STOT SE 3 (70%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.