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Atomfair Aspartame Acesulfame [‘Twinsweet’, ‘APM-ACE’, ‘E-962’, ‘INS-962’] C18H23N3O9S CAS 106372-55-8

Aspartame Acesulfame (CAS: 106372-55-8) is a high-intensity artificial sweetener blend composed of aspartame and acesulfame potassium in a 1:1 molar ratio. This synergistic combination provides enhanced sweetness (approximately 350 times sweeter than sucrose) with improved stability and reduced bitter aftertaste compared to individual components. The molecular formula C18H23N3O9S represents this co-crystallized salt, which meets USP/NF, FCC, and food additive specifications (INS No. 962, E-962). Key advantages include: Heat-stable formulation suitable for baked goods (up to 200°C) Zero-calorie profile with rapid sweetness onset Excellent solubility in water (≥100 mg/mL at 20°C) pH stability range of 2-7 for beverage applications Certified Kosher…

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Description

Aspartame Acesulfame (CAS: 106372-55-8) is a high-intensity artificial sweetener blend composed of aspartame and acesulfame potassium in a 1:1 molar ratio. This synergistic combination provides enhanced sweetness (approximately 350 times sweeter than sucrose) with improved stability and reduced bitter aftertaste compared to individual components. The molecular formula C18H23N3O9S represents this co-crystallized salt, which meets USP/NF, FCC, and food additive specifications (INS No. 962, E-962).

Key advantages include:

  • Heat-stable formulation suitable for baked goods (up to 200°C)
  • Zero-calorie profile with rapid sweetness onset
  • Excellent solubility in water (≥100 mg/mL at 20°C)
  • pH stability range of 2-7 for beverage applications
  • Certified Kosher and Halal compliant options available

Packaged in pharmaceutical-grade HDPE containers with nitrogen flush for maximum shelf life (36 months when stored at ≤25°C/60% RH). Available in bulk quantities from 1kg to palletized 25kg drums with custom granulation options.

Properties

  • CAS Number: 106372-55-8
  • Complexity: 662
  • IUPAC Name: (3S)-3-amino-4-[[(1S)-1-benzyl-2-methoxy-2-oxo-ethyl]amino]-4-oxo-butanoic acid;6-methyl-2,2-dioxo-oxathiazin-4-one
  • InChI: InChI=1S/C14H18N2O5.C4H5NO4S/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18;1-3-2-4(6)5-10(7,8)9-3/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18);2H,1H3,(H,5,6)/t10-,11-;/m0./s1
  • InChI Key: KVHQNWGLVVERFR-ACMTZBLWSA-N
  • Exact Mass: 457.11550049
  • Molecular Formula: C18H23N3O9S
  • Molecular Weight: 457.5
  • SMILES: CC1=CC(=O)NS(=O)(=O)O1.COC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)O)N
  • Topological: 200
  • Monoisotopic Mass: 457.11550049
  • Physical Description: A white, odourless, crystalline powder
  • Solubility: Sparingly soluble water; slightly soluble in ethanol
  • Synonyms: Aspartame Acesulfame, Twinsweet, Aspartame acesulfame [NF], UNII-IFE6C6BS24, IFE6C6BS24, TWINSWEET LA, APM-ACE, Aspartame-acesulfame salt, Aspartame acesulfame (NF), INS NO.962, DTXSID30909991, INS-962, SALT OF ASPARTAME-ACESULFAME, ASPARTAME ACESULFAME [MART.], ASPARTAME ACESULFAME [USP-RS], ASPARTAME-ACESULFAME SALT [FCC], E-962, ASPARTAME ACESULFAME (MART.), ASPARTAME ACESULFAME (USP-RS), (2-CARBOXY–(N-(B-METHOXYCARBONYL-2 PHENYL)ETHYLCARBAMOYL)) ETHANAMINIUM 6-METHYL-4-OXO-1,2,3-OXATHIAZIN-3-IDE-2,2-DIOXIDE, L-PHENYLALANINE, L-.ALPHA.-ASPARTYL-2-METHYL ESTER COMPOUND WITH 6-METHYL-1,2,3-OXATHIAZIN-4(3H)-ONE 2,2-DIOXIDE (1:1), L-Phenylalanine, L-alpha-aspartyl-2-methyl ester compound with 6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide (1:1), DTXCID401341346, Aspartame-acesulfameAspartame-acesulfame salt, 106372-55-8, Acesulfame Aspartame Salt, (3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid;6-methyl-2,2-dioxooxathiazin-4-one, 6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide (S)-3-amino-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoate, Acesulfame Aspartame Salt; Aspartame Acesulfame, Aspartame acesulfame salt, SCHEMBL875414, AKOS040750602, ASPARTAME ACESULFAME (200 MG), DA-50746, HY-118347, CS-0065729, D08862, Q409847, (2-Carboxy-beta-(N-b-methoxycarbonyl-2-phenyl)ethylcarbamoyl))ethanaminium 6-methyl-4-oxo-1,2,3-oxathiazin-3-ide-2,2-dioxide, (3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoate;6-methyl-2,2-dioxooxathiazin-3-ium-4-one

Aspartame Acesulfame is widely used as a sugar substitute in low-calorie foods and beverages, including carbonated drinks, dairy products, and confectionery. The blend’s synergistic properties make it ideal for pharmaceutical formulations requiring stable, high-intensity sweetening. Industrial applications include tabletop sweeteners and functional food products targeting diabetic consumers.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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