Atomfair 2-Bromo-5-methoxypyridine C6H6BrNO CAS 105170-27-2

Description

2-Bromo-5-methoxypyridine (CAS No. 105170-27-2) is a high-purity heterocyclic compound with the molecular formula C₆H₆BrNO. This versatile intermediate is widely used in pharmaceutical, agrochemical, and material science research due to its reactive bromine and methoxy functional groups. The compound is supplied as a white to off-white crystalline powder with a purity of ≥98% (HPLC), ensuring optimal performance in synthetic applications. Its stability under standard laboratory conditions and compatibility with a range of solvents make it a reliable choice for cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings. Each batch undergoes rigorous QC testing (GC/MS, NMR) to guarantee consistency and traceability for research applications. Available in scalable quantities from milligrams to kilograms, it is ideal for both small-scale experimentation and industrial-scale production.

Properties

• CAS Number: 105170-27-2
• Complexity: 89.1
• IUPAC Name: 2-bromo-5-methoxy-pyridine
• InChI: InChI=1S/C6H6BrNO/c1-9-5-2-3-6(7)8-4-5/h2-4H,1H3
• InChI Key: WULVUFYZVYHTFX-UHFFFAOYSA-N
• Exact Mass: 186.96328
• Molecular Formula: C6H6BrNO
• Molecular Weight: 188.02
• SMILES: COC1=CN=C(C=C1)Br
• Topological: 22.1
• Monoisotopic Mass: 186.96328
• Synonyms: 2-Bromo-5-methoxypyridine, 105170-27-2, DTXSID40456885, DTXCID70407704, 695-886-4, 2-bromo-5-methoxy-pyridine, MFCD07781221, PYRIDINE, 2-BROMO-5-METHOXY-, 6-Bromo-3-methoxypyridine, 2-bromo-5-methoxy pyridine, SCHEMBL502881, SCHEMBL1761608, SCHEMBL17007172, WULVUFYZVYHTFX-UHFFFAOYSA-N, BCP04838, CS-D1766, BBL101467, STL555263, AKOS005199441, PB22062, PS-4907, SY022318, DB-024968, B5910, EN300-75739

2-Bromo-5-methoxypyridine serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development. Its bromine moiety enables efficient palladium-catalyzed cross-coupling reactions for constructing complex heterocycles. Researchers also utilize it in agrochemical synthesis for crop protection agents. The methoxy group enhances solubility and modulates electronic properties in material science applications, such as OLED precursors. Strictly for research use—not for drug, household, or other unintended applications.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (75%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (75%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.