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Atomfair 2-Amino-6-chloropurine 6-Cl-Guanine, 6CGP C5H4ClN5 CAS 10310-21-1

2-Amino-6-chloropurine (CAS No. 10310-21-1) is a high-purity heterocyclic organic compound with the molecular formula C5H4ClN5. This chlorinated purine derivative serves as a critical intermediate in pharmaceutical synthesis, nucleoside chemistry, and biochemical research. With a purity of ≥99%, our product is rigorously tested via HPLC, NMR, and mass spectrometry to ensure compliance with industry standards. It is supplied as an off-white to light yellow crystalline powder with excellent solubility in DMSO and moderate solubility in methanol. Ideal for medicinal chemistry applications, this compound is widely utilized in the development of antiviral agents, anticancer drugs, and as a precursor for modified nucleosides.…

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Description

2-Amino-6-chloropurine (CAS No. 10310-21-1) is a high-purity heterocyclic organic compound with the molecular formula C5H4ClN5. This chlorinated purine derivative serves as a critical intermediate in pharmaceutical synthesis, nucleoside chemistry, and biochemical research. With a purity of ≥99%, our product is rigorously tested via HPLC, NMR, and mass spectrometry to ensure compliance with industry standards. It is supplied as an off-white to light yellow crystalline powder with excellent solubility in DMSO and moderate solubility in methanol. Ideal for medicinal chemistry applications, this compound is widely utilized in the development of antiviral agents, anticancer drugs, and as a precursor for modified nucleosides. Store under inert conditions at 2-8°C for maximum stability.

Properties

  • CAS Number: 10310-21-1
  • Complexity: 154
  • IUPAC Name: 6-chloro-7H-purin-2-amine
  • InChI: InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)
  • InChI Key: RYYIULNRIVUMTQ-UHFFFAOYSA-N
  • Exact Mass: 169.0155228
  • Molecular Formula: C5H4ClN5
  • Molecular Weight: 169.57
  • SMILES: C1=NC2=C(N1)C(=NC(=N2)N)Cl
  • Topological: 80.5
  • Monoisotopic Mass: 169.0155228
  • Synonyms: 2-Amino-6-chloropurine, 10310-21-1, 6-Chloroguanine, 6-chloro-7H-purin-2-amine, 6-Chloro-2-aminopurine, 2-Amino-6-chlorpurine, Purine, 2-amino-6-chloro-, 1H-Purin-2-amine, 6-chloro-, 6-Chloro-7H-purin-2-ylamine, 2-amino-6-chloro-9h-purine, 6-CHLORO-1H-PURIN-2-AMINE, 6-Chloro-2-purinamine, 9H-Purin-2-amine, 6-chloro-, EINECS 233-686-7, NSC 29570, CHEBI:72345, NSC-29570, 83V03P835E, DTXSID9074432, 6-CHLORO-9H-PURIN-2-YL-2-AMINE, DTXCID0032786, 1H-Purin-2-amine, 6-chloro-(9CI), 6-Chloro-9H-purin-2-amine, 2-Amino-6-Chloro-Purin, MFCD00075252, 2-Amino-6-chloropurin-9-yl, 6-chloro-9h-purin-2-ylamine, CHEMBL226396, 6-chloropurine-2-ylamine, 133762-81-9, 2-amino-6-chloro-purine, CCRIS 3906, UNII-83V03P835E, 6GU, 2-amino-6chloropurine, 6-Cl-purine (1), 2-Amino-6-chloropurine (6-Chloroguanine), 6-chloro-2-amino-purine, bmse000984, SCHEMBL6711, SCHEMBL64059, 6-chloro-9h-purine-2-amine, MLS006011426, 6-chloro-1H-purine-2-amine, SCHEMBL536979, SCHEMBL2698213, SCHEMBL3268234, SCHEMBL6323165, 2-Amino-6-chloropurine, 97%, 6-Chloro-9H-purin-2-amine #, 2-Amino-6-chloropurine, >=99%, ALBB-023676, BCP27028, CS-D1374, HY-Y0429, NSC29570, AB2611, BBL010748, BDBM50208877, SBB003863, STK801756, AKOS000266285, AKOS005622720, AKOS028108866, AC-5457, AS-2051, FA02581, 6-Chloro-2-purinamine, 6-Chloroguanine, PD130981, SMR002529527, SY001781, DB-005179, A1407, NS00015540, ST45026866, EN300-94711, SR-01000944797, SR-01000944797-1, Q27139921, F0001-0084, Z2472857685

2-Amino-6-chloropurine is extensively used as a building block in nucleoside analog synthesis for antiviral and antitumor research. It serves as a key intermediate in the production of guanine derivatives and modified DNA/RNA bases. Researchers employ this compound in kinase inhibition studies and as a precursor for fluorescent nucleoside probes. Its chloropurine structure makes it valuable for cross-coupling reactions in medicinal chemistry workflows.

Safety and Hazards

GHS Hazard Statements

  • Not Classified
  • Reported as not meeting GHS hazard criteria by 37 of 42 companies

Hazard Classes and Categories

  • Not Classified

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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