Description

4-Chloro-3-nitroanisole (CAS No. 10298-80-3) is a high-purity nitroaromatic compound with the molecular formula C₇H₆ClNO₃ and IUPAC name 1-chloro-4-methoxy-2-nitrobenzene. This yellow to pale brown crystalline solid is widely utilized in organic synthesis, pharmaceutical intermediates, and agrochemical research. With a molecular weight of 187.58 g/mol, it exhibits excellent stability under standard conditions and is soluble in common organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO). Our product is rigorously tested to ensure ≥98% purity (HPLC) and is supplied in sealed, light-resistant containers to maintain integrity. Ideal for nucleophilic substitution reactions and as a precursor for dyes, pigments, and specialty chemicals. Available in research (1g-100g) and bulk quantities (1kg+) with customizable packaging options.

Properties

• CAS Number: 10298-80-3
• Complexity: 171
• IUPAC Name: 1-chloro-4-methoxy-2-nitro-benzene
• InChI: InChI=1S/C7H6ClNO3/c1-12-5-2-3-6(8)7(4-5)9(10)11/h2-4H,1H3
• InChI Key: HISHUMDTGXICEZ-UHFFFAOYSA-N
• Exact Mass: 187.0036207
• Molecular Formula: C7H6ClNO3
• Molecular Weight: 187.58
• SMILES: COC1=CC(=C(C=C1)Cl)[N+](=O)[O-]
• Topological: 55.1
• Monoisotopic Mass: 187.0036207
• Synonyms: 4-Chloro-3-nitroanisole, 1-Chloro-4-methoxy-2-nitrobenzene, Benzene, 1-chloro-4-methoxy-2-nitro-, Benzene, 1-chloro-4-methoxy-2-nitro-(9CI), 233-674-1, 10298-80-3, 2-Chloro-5-methoxynitrobenzene, ANISOLE, 4-CHLORO-3-NITRO-, 1-Chloro-4-methoxy-2-nitro-Benzene, MFCD00007077, NSC-47339, EINECS 233-674-1, NSC 47339, BRN 0640872, NSC 47339; 1-Chloro-4-methoxy-2-nitrobenzene; 2-Nitro-4-methoxychlorobenzene, NSC47339, 4-chloro-3-nitroanisol, 4-chloro-3-nitro-anisole, WLN: WNR BG EO1, 3UJ5FB5WT5, 4-06-00-01352 (Beilstein Handbook Reference), SCHEMBL541479, 4-Chloro-3-nitroanisole, 98%, DTXSID80145600, BBL000390, SBB065038, STK802942, AKOS000114112, CS-W001190, PS-5413, AC-25980, SY008115, DB-023680, C1225, NS00023199, ST45053767, EN300-16633

Application

4-Chloro-3-nitroanisole serves as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antimicrobial and anti-inflammatory agents. It is employed in agrochemical research for creating herbicidal and pesticidal compounds through further functionalization. The compound’s nitro and chloro groups make it valuable for Suzuki coupling and other palladium-catalyzed cross-coupling reactions in material science applications.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.8%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.