Description
3-Methyl-2-phenylpyridine (CAS No. 10273-90-2) is a high-purity heterocyclic organic compound with the molecular formula C12H11N. This specialized chemical features a pyridine ring substituted with a methyl group at the 3-position and a phenyl group at the 2-position, offering unique electronic and steric properties for advanced research applications. Available in various quantities with ≥98% purity (HPLC/GC), it is ideal for pharmaceutical intermediates, ligand synthesis, and material science research. The compound is supplied in sealed, light-resistant containers under inert gas to ensure stability. Technical data including 1H/13C NMR spectra, mass spectrometry, and HPLC chromatograms are available upon request. Store at 2-8°C in a dry environment.
Properties
- CAS Number: 10273-90-2
- Complexity: 149
- IUPAC Name: 3-methyl-2-phenyl-pyridine
- InChI: InChI=1S/C12H11N/c1-10-6-5-9-13-12(10)11-7-3-2-4-8-11/h2-9H,1H3
- InChI Key: BJATUPPYBZHEIO-UHFFFAOYSA-N
- Exact Mass: 169.089149355
- Molecular Formula: C12H11N
- Molecular Weight: 169.22
- SMILES: CC1=C(N=CC=C1)C2=CC=CC=C2
- Topological: 12.9
- Monoisotopic Mass: 169.089149355
- Synonyms: 3-Methyl-2-phenylpyridine, 10273-90-2, Pyridine, 3-methyl-2-phenyl-, 3-Picoline, 2-phenyl-, OIY9I0GL3Z, EINECS 233-619-1, NSC 26784, NSC-26784, DTXSID50145475, DTXCID1067966, 233-619-1, MFCD00006283, 3-methyl-2-phenyl-pyridine, 2-Phenyl-beta-picoline, 2-Phenyl-3-methyl-pyridine, NSC26784, UNII-OIY9I0GL3Z, SCHEMBL64623, SCHEMBL1521695, SCHEMBL1521697, SCHEMBL2871935, SCHEMBL7374780, SCHEMBL9871308, BJATUPPYBZHEIO-UHFFFAOYSA-, 3-Methyl-2-phenylpyridine, 98%, AKOS015841925, CS-W017719, SB52471, DS-10693, SY019480, M0932, NS00023175, InChI=1/C12H11N/c1-10-6-5-9-13-12(10)11-7-3-2-4-8-11/h2-9H,1H3
Application
3-Methyl-2-phenylpyridine serves as a key building block in medicinal chemistry for developing kinase inhibitors and CNS-active compounds. Its sterically hindered pyridine core facilitates chelation in transition metal catalyst systems for cross-coupling reactions. Researchers utilize this compound in OLED material development due to its electron-transporting characteristics and thermal stability.
Safety and Hazards
GHS Hazard Statements
- H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H318 (97.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
- H335 (97.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Acute Tox. 4 (97.5%)
- Skin Irrit. 2 (100%)
- Eye Dam. 1 (97.5%)
- STOT SE 3 (97.5%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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