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Atomfair Trimethylsilyl triflate TMSOTf C4H9F3O3SSi

Description Trimethylsilyl triflate (CAS No. 27607-77-8) is a highly reactive organosilicon compound with the molecular formula C4H9F3O3SSi . Also known as trimethylsilyl trifluoromethanesulfonate , it is a powerful silylating agent and Lewis acid catalyst widely used in organic synthesis. This colorless to pale yellow liquid is moisture-sensitive and should be stored under inert conditions. Its exceptional reactivity makes it invaluable for introducing trimethylsilyl groups, activating hydroxyl groups, and facilitating glycosylation reactions. With a purity typically exceeding 98%, our product is rigorously tested to meet the stringent requirements of pharmaceutical, materials science, and academic research applications. Available in various packaging options…

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Description

Description

Trimethylsilyl triflate (CAS No. 27607-77-8) is a highly reactive organosilicon compound with the molecular formula C4H9F3O3SSi. Also known as trimethylsilyl trifluoromethanesulfonate, it is a powerful silylating agent and Lewis acid catalyst widely used in organic synthesis. This colorless to pale yellow liquid is moisture-sensitive and should be stored under inert conditions. Its exceptional reactivity makes it invaluable for introducing trimethylsilyl groups, activating hydroxyl groups, and facilitating glycosylation reactions. With a purity typically exceeding 98%, our product is rigorously tested to meet the stringent requirements of pharmaceutical, materials science, and academic research applications. Available in various packaging options under argon atmosphere to ensure stability.

  • CAS No: 27607-77-8
  • Molecular Formula: C4H9F3O3SSi
  • Molecular Weight: 222.26
  • Exact Mass: 221.99937634
  • Monoisotopic Mass: 221.99937634
  • IUPAC Name: trimethylsilyl trifluoromethanesulfonate
  • SMILES: C[Si](C)(C)OS(=O)(=O)C(F)(F)F
  • Synonyms: Trimethylsilyl trifluoromethanesulfonate, 27607-77-8, Trimethylsilyl triflate, Trimethylsilyl trifluoromethanesulphonate, Trimethylsilyl trifluoromethylsulfonate

Application

Trimethylsilyl triflate is extensively employed as a catalyst in glycosylation reactions for carbohydrate chemistry. It serves as an effective silylating agent for protecting alcohols and other functional groups in complex organic syntheses. The compound finds particular utility in nucleoside and steroid chemistry due to its ability to activate hydroxyl groups under mild conditions.

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