Description

Description

Trifluoro(pyrrolidin-1-ylmethyl)boranuide (CAS No. 1686150-29-7) is a highly specialized boron-based anionic compound with the molecular formula C₅H₁₀BF₃N^–. This organoboron reagent features a pyrrolidine-substituted methyl group bonded to a trifluoroborate anion, offering unique reactivity in synthetic chemistry applications. The compound is supplied as a high-purity material suitable for use as a nucleophilic trifluoroborate reagent in cross-coupling reactions, particularly in Suzuki-Miyaura couplings where its enhanced stability compared to boronic acids is advantageous. With its well-defined structure and consistent performance, this chemical is ideal for pharmaceutical research, materials science, and advanced organic synthesis. Proper handling under inert atmosphere is recommended due to potential sensitivity to moisture and air.

Application

Trifluoro(pyrrolidin-1-ylmethyl)boranuide serves as a stable trifluoroborate reagent for transition metal-catalyzed cross-coupling reactions in medicinal chemistry. Its enhanced stability compared to boronic acids makes it valuable for Suzuki-Miyaura couplings in drug discovery pipelines. The compound finds particular utility in the synthesis of complex molecules where traditional boronic acids may decompose. Researchers also employ this reagent in the development of boron-containing materials with tailored electronic properties.

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