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Atomfair Tert-butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate C12H24N2O2

Description Tert-butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate (CAS No. 1357600-61-3) is a high-purity, synthetic organic compound with the molecular formula C12H24N2O2. This Boc-protected piperidine derivative features a tertiary butyl carbamate group and a primary amine at the 4-position, making it a versatile intermediate in pharmaceutical and agrochemical synthesis. Its rigid, sterically hindered structure enhances selectivity in coupling reactions and chiral transformations. The compound is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring optimal performance in demanding applications. Store under inert conditions at 2-8??C to maintain stability. Suitable for use in medicinal chemistry, peptidomimetics, and as a building block for…

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Description

Description

Tert-butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate (CAS No. 1357600-61-3) is a high-purity, synthetic organic compound with the molecular formula C12H24N2O2. This Boc-protected piperidine derivative features a tertiary butyl carbamate group and a primary amine at the 4-position, making it a versatile intermediate in pharmaceutical and agrochemical synthesis. Its rigid, sterically hindered structure enhances selectivity in coupling reactions and chiral transformations. The compound is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring optimal performance in demanding applications. Store under inert conditions at 2-8??C to maintain stability. Suitable for use in medicinal chemistry, peptidomimetics, and as a building block for kinase inhibitors and GPCR-targeted therapeutics.

  • CAS No: 1357600-61-3
  • Molecular Formula: C12H24N2O2
  • Molecular Weight: 228.33
  • Exact Mass: 228.183778013
  • Monoisotopic Mass: 228.183778013
  • IUPAC Name: tert-butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate
  • SMILES: CC1(CN(CCC1N)C(=O)OC(C)(C)C)C
  • Synonyms: 473838-65-2, TERT-BUTYL 4-AMINO-3,3-DIMETHYLPIPERIDINE-1-CARBOXYLATE, DTXSID80436323, DTXCID20387148, 824-563-4

Application

Tert-butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate serves as a critical scaffold in the development of protease inhibitors and allosteric modulators due to its constrained geometry. The Boc-protected amine enables selective deprotection for sequential functionalization in multi-step syntheses. Researchers utilize this compound in fragment-based drug discovery, particularly for targeting neurological and metabolic disorders. Its steric profile makes it valuable for constructing quaternary carbon centers in complex natural product syntheses.

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