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Atomfair (S)-Bis(4-fluorophenyl)(pyrrolidin-2-yl)methanol C17H17F2NO

Description (S)-Bis(4-fluorophenyl)(pyrrolidin-2-yl)methanol (CAS No. 131180-45-5) is a high-purity chiral compound with the molecular formula C17H17F2NO . This fluorinated pyrrolidine derivative is a valuable building block in asymmetric synthesis and pharmaceutical research, particularly in the development of bioactive molecules and enantioselective catalysts. The compound features two para -fluorophenyl groups and a stereogenic center at the pyrrolidine-2-ylmethanol moiety, making it a versatile intermediate for medicinal chemistry and drug discovery. Supplied as a white to off-white crystalline solid, it is characterized by HPLC/GC-MS for purity (>97%) and is stored under inert conditions to ensure stability. Ideal for researchers in organocatalysis, neuropharmacology, and fluorinated…

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Description

Description

(S)-Bis(4-fluorophenyl)(pyrrolidin-2-yl)methanol (CAS No. 131180-45-5) is a high-purity chiral compound with the molecular formula C17H17F2NO. This fluorinated pyrrolidine derivative is a valuable building block in asymmetric synthesis and pharmaceutical research, particularly in the development of bioactive molecules and enantioselective catalysts. The compound features two para-fluorophenyl groups and a stereogenic center at the pyrrolidine-2-ylmethanol moiety, making it a versatile intermediate for medicinal chemistry and drug discovery. Supplied as a white to off-white crystalline solid, it is characterized by HPLC/GC-MS for purity (>97%) and is stored under inert conditions to ensure stability. Ideal for researchers in organocatalysis, neuropharmacology, and fluorinated compound studies.

  • CAS No: 131180-45-5
  • Molecular Formula: C17H17F2NO
  • Molecular Weight: 289.32
  • Exact Mass: 289.12782049
  • Monoisotopic Mass: 289.12782049
  • IUPAC Name: bis(4-fluorophenyl)-pyrrolidin-2-ylmethanol
  • SMILES: C1CC(NC1)C(C2=CC=C(C=C2)F)(C3=CC=C(C=C3)F)O
  • Synonyms: (S)-Bis(4-fluorophenyl)(pyrrolidin-2-yl)methanol, bis(4-fluorophenyl)[(2S)-pyrrolidin-2-yl]methanol, SCHEMBL1408642, HMS3318F05

Application

(S)-Bis(4-fluorophenyl)(pyrrolidin-2-yl)methanol is widely used as a chiral scaffold in the synthesis of dopamine receptor ligands and other CNS-targeting pharmaceuticals. Its fluorinated aromatic groups enhance metabolic stability, making it valuable for probing structure-activity relationships in drug design. The compound also serves as a precursor for enantioselective catalysts in asymmetric C-C bond-forming reactions.

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