Atomfair

Awaiting product image

Atomfair Ranirestat AS-3201 C17H11BrFN3O4

Description Ranirestat (CAS No. 147254-64-6) is a high-purity small molecule inhibitor with the molecular formula C17H11BrFN3O4. Its IUPAC name is (3R)-2′-[(4-bromo-2-fluorophenyl)methyl]spiro[pyrrolidine-3,4′-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5-tetrone . This compound is a potent and selective aldose reductase inhibitor, designed for research applications in diabetic complications, particularly neuropathy. Ranirestat is supplied as a lyophilized powder with ??98% purity (HPLC), ensuring optimal consistency for biochemical and pharmacological studies. Suitable for in vitro and in vivo research, it is packaged under inert conditions to guarantee stability. Store at -20??C, protected from light and moisture.

Category:
Brands:

Description

Description

Ranirestat (CAS No. 147254-64-6) is a high-purity small molecule inhibitor with the molecular formula C17H11BrFN3O4. Its IUPAC name is (3R)-2′-[(4-bromo-2-fluorophenyl)methyl]spiro[pyrrolidine-3,4′-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5-tetrone. This compound is a potent and selective aldose reductase inhibitor, designed for research applications in diabetic complications, particularly neuropathy. Ranirestat is supplied as a lyophilized powder with ??98% purity (HPLC), ensuring optimal consistency for biochemical and pharmacological studies. Suitable for in vitro and in vivo research, it is packaged under inert conditions to guarantee stability. Store at -20??C, protected from light and moisture.

  • CAS No: 147254-64-6
  • Molecular Formula: C17H11BrFN3O4
  • Molecular Weight: 420.2
  • Exact Mass: 418.99170
  • Monoisotopic Mass: 418.99170
  • IUPAC Name: (3R)-2′-[(4-bromo-2-fluorophenyl)methyl]spiro[pyrrolidine-3,4′-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5-tetrone
  • SMILES: C1C(=O)NC(=O)[C@@]12C(=O)N(C(=O)C3=CC=CN23)CC4=C(C=C(C=C4)Br)F
  • Synonyms: Ranirestat, 147254-64-6, AS-3201, Ranirestat [INN], Z26P56GFTV

Application

Ranirestat is primarily investigated for its role in inhibiting aldose reductase, a key enzyme in the polyol pathway implicated in diabetic complications. Researchers utilize it to study its neuroprotective effects in diabetic neuropathy models. Its mechanism may also be relevant for exploring oxidative stress and inflammatory pathways in metabolic disorders.

If you are interested or have any questions, please contact us at support@atomfair.com