Description

Description

Phenyl Methanesulfonate (CAS No. 16156-59-5) is a high-purity organic sulfonate ester with the molecular formula C₇H₈O₃S. This compound, also known by its IUPAC name phenyl methanesulfonate, is a versatile reagent widely used in organic synthesis, pharmaceutical research, and material science. It features a methanesulfonate (mesylate) group bonded to a phenyl ring, offering excellent reactivity as an alkylating or sulfonating agent. Our product is rigorously tested for purity (typically ??98% by HPLC) and is supplied as a clear to pale-yellow liquid with minimal moisture content. Suitable for use under inert atmospheres, it is packaged in amber glass bottles to ensure stability. Ideal for nucleophilic substitution reactions, cross-coupling protocols, and as a precursor for advanced intermediates.

Application

Phenyl Methanesulfonate is commonly employed as an electrophilic reagent in organic synthesis, particularly in nucleophilic aromatic substitution reactions. It serves as a key intermediate in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. Researchers utilize it in Suzuki-Miyaura and other cross-coupling reactions due to its reactive mesylate leaving group. Additionally, it finds use in polymer chemistry as a modifying agent for aromatic monomers.

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