Description

Description

p-Tolueneboronic acid (CAS No. 30418-59-8), also known as p-Tolylboronic acid, is a high-purity aromatic boronic acid derivative with the molecular formula C₇H₉BO₂. This white to off-white crystalline powder is a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, where it serves as a key reagent for the formation of carbon-carbon bonds. With a molecular weight of 135.96 g/mol, it exhibits excellent stability under standard conditions and is soluble in common organic solvents such as THF, DMSO, and methanol. Ideal for pharmaceutical, agrochemical, and materials science research, our p-Tolueneboronic acid is rigorously tested to ensure ??98% purity (HPLC) and is supplied with detailed analytical documentation, including ¹H NMR and ¹³C NMR spectra. Packaged under inert gas to prevent moisture absorption, this reagent is a must-have for synthetic chemists working on aryl-aryl bond formations and functional group transformations.

Application

p-Tolueneboronic acid is widely used as a coupling partner in Suzuki-Miyaura cross-coupling reactions to synthesize biaryl compounds, a critical step in drug discovery and material science. It serves as a precursor for functionalized aromatics in pharmaceuticals, such as kinase inhibitors and NSAID derivatives. In materials chemistry, it enables the synthesis of ??-conjugated polymers for OLEDs and organic electronics. Additionally, it is employed in protodeboronation studies and as a ligand in transition metal catalysis.

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