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Atomfair o-Phenylene phosphorochloridate C6H4ClO3P
Description o-Phenylene phosphorochloridate (CAS #1522-41-4) is a highly specialized organophosphorus compound with the molecular formula C6H4ClO3P and IUPAC name 2-chloro-1,3,2??5-benzodioxaphosphole 2-oxide . This heterocyclic reagent features a reactive phosphorus-chloride bond, making it a valuable intermediate in synthetic organic and organophosphorus chemistry. Its rigid o-phenylene backbone enhances stability while allowing selective reactivity. Supplied as a high-purity solid or solution, it is rigorously tested via31P NMR, HPLC, and elemental analysis to ensure consistency for demanding applications. Ideal for phosphorylation reactions, ligand synthesis, and as a precursor for flame retardants or bioactive molecules. Handle under inert atmosphere due to moisture sensitivity. Available in…
Description
Description
o-Phenylene phosphorochloridate (CAS #1522-41-4) is a highly specialized organophosphorus compound with the molecular formula C6H4ClO3P and IUPAC name 2-chloro-1,3,2??5-benzodioxaphosphole 2-oxide. This heterocyclic reagent features a reactive phosphorus-chloride bond, making it a valuable intermediate in synthetic organic and organophosphorus chemistry. Its rigid o-phenylene backbone enhances stability while allowing selective reactivity. Supplied as a high-purity solid or solution, it is rigorously tested via 31P NMR, HPLC, and elemental analysis to ensure consistency for demanding applications. Ideal for phosphorylation reactions, ligand synthesis, and as a precursor for flame retardants or bioactive molecules. Handle under inert atmosphere due to moisture sensitivity. Available in research (gram) to bulk (kilogram) quantities with custom packaging options.
- CAS No: 1522-41-4
- Molecular Formula: C6H4ClO3P
- Molecular Weight: 190.52
- Exact Mass: 189.9586587
- Monoisotopic Mass: 189.9586587
- IUPAC Name: 2-chloro-1,3,2lambda5-benzodioxaphosphole 2-oxide
- SMILES: C1=CC=C2C(=C1)OP(=O)(O2)Cl
- Synonyms: 1499-17-8, 1,3,2-Benzodioxaphosphole, 2-chloro-, 2-oxide, o-Phenylene phosphorochloridate, 1,2-PHENYLENE PHOSPHOROCHLORIDATE, 2-Chloro-1,3,2-benzodioxaphosphole 2-oxide
Application
o-Phenylene phosphorochloridate serves as a key electrophilic phosphorylating agent in nucleotide and phosphoramidite synthesis. It is employed in the preparation of cyclic phosphate esters for flame-retardant polymers and as a precursor for chiral phosphite ligands in asymmetric catalysis. Researchers utilize it to construct phosphorus-containing heterocycles for agrochemical and pharmaceutical development. Its reactivity is particularly valued in modifying biomolecules and creating organocatalysts.
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