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Atomfair Nadolol [USAN:USP:INN:BAN:JAN] C17H27NO4

Description Nadolol (CAS No. 455-13-0) is a non-selective beta-adrenergic receptor blocker with the molecular formula C17H27NO4and IUPAC name 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol . This white to off-white crystalline powder is a clinically significant pharmaceutical compound widely used in cardiovascular therapeutics. As a beta-blocker, Nadolol exhibits both antihypertensive and antianginal properties, making it valuable for managing hypertension, angina pectoris, and certain arrhythmias. Its unique chemical structure features a naphthalene ring system with multiple hydroxyl groups, contributing to its pharmacological profile. This high-purity reference standard is ideal for analytical testing, pharmaceutical research, and method development in HPLC, LC-MS, and spectroscopic applications. Supplied with comprehensive analytical…

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Description

Description

Nadolol (CAS No. 455-13-0) is a non-selective beta-adrenergic receptor blocker with the molecular formula C17H27NO4 and IUPAC name 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol. This white to off-white crystalline powder is a clinically significant pharmaceutical compound widely used in cardiovascular therapeutics. As a beta-blocker, Nadolol exhibits both antihypertensive and antianginal properties, making it valuable for managing hypertension, angina pectoris, and certain arrhythmias. Its unique chemical structure features a naphthalene ring system with multiple hydroxyl groups, contributing to its pharmacological profile. This high-purity reference standard is ideal for analytical testing, pharmaceutical research, and method development in HPLC, LC-MS, and spectroscopic applications. Supplied with comprehensive analytical data including NMR and HPLC chromatograms to ensure quality and traceability.

  • CAS No: 455-13-0
  • Molecular Formula: C17H27NO4
  • Molecular Weight: 309.4
  • Exact Mass: 309.19400834
  • Monoisotopic Mass: 309.19400834
  • IUPAC Name: 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol
  • SMILES: CC(C)(C)NCC(COC1=CC=CC2=C1CC(C(C2)O)O)O
  • Synonyms: Nadololum [INN-Latin], CCRIS 1048, HSDB 6532, EINECS 255-706-3, Nadolol [USAN:USP:INN:BAN:JAN]

Application

Nadolol is primarily used in clinical research and pharmaceutical development as a beta-adrenergic antagonist. It demonstrates effectiveness in managing hypertension by reducing cardiac output and peripheral resistance. Researchers utilize this compound in studies of cardiovascular pharmacology, particularly in investigating beta-blocker mechanisms and receptor interactions. Its long half-life makes it valuable for sustained therapeutic effect studies.

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