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Atomfair N(4)-(1(b),2(a),3(a)-Trihydroxy-4(b)-1,2,3,4-tetrahydronaphthyl)-2′-deoxycytidine Tthn-DC C19H23N3O7

Description N(4)-(1(b),2(a),3(a)-Trihydroxy-4(b)-1,2,3,4-tetrahydronaphthyl)-2′-deoxycytidine (CAS No. 1570-95-2) is a specialized nucleoside derivative with the molecular formula C19H23N3O7. This compound features a unique tetrahydronaphthalene moiety linked to a 2′-deoxycytidine scaffold, making it a valuable intermediate for biochemical and pharmaceutical research. Its IUPAC name, 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-[(2,3,4-trihydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino]pyrimidin-2-one , highlights its complex stereochemistry and functional group diversity. Researchers utilize this compound in studies involving nucleoside modifications, DNA interactions, and enzyme inhibition. Available with >95% purity (HPLC), it is supplied as a lyophilized powder under inert packaging to ensure stability.

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Description

Description

N(4)-(1(b),2(a),3(a)-Trihydroxy-4(b)-1,2,3,4-tetrahydronaphthyl)-2′-deoxycytidine (CAS No. 1570-95-2) is a specialized nucleoside derivative with the molecular formula C19H23N3O7. This compound features a unique tetrahydronaphthalene moiety linked to a 2′-deoxycytidine scaffold, making it a valuable intermediate for biochemical and pharmaceutical research. Its IUPAC name, 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-[(2,3,4-trihydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino]pyrimidin-2-one, highlights its complex stereochemistry and functional group diversity. Researchers utilize this compound in studies involving nucleoside modifications, DNA interactions, and enzyme inhibition. Available with >95% purity (HPLC), it is supplied as a lyophilized powder under inert packaging to ensure stability.

  • CAS No: 1570-95-2
  • Molecular Formula: C19H23N3O7
  • Molecular Weight: 405.4
  • Exact Mass: 405.15360008
  • Monoisotopic Mass: 405.15360008
  • IUPAC Name: 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-[(2,3,4-trihydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino]pyrimidin-2-one
  • SMILES: C1C(C(OC1N2C=CC(=NC2=O)NC3C(C(C(C4=CC=CC=C34)O)O)O)CO)O
  • Synonyms: Tthn-DC, 135269-59-9, N(4)-(1(b),2(a),3(a)-Trihydroxy-4(b)-1,2,3,4-tetrahydronaphthyl)-2′-deoxycytidine, (1R-(1alpha,2beta,3beta,4alpha))-2′-Deoxy-N-(1,2,3,4-tetrahydro-2,3,4-trihydroxy-1-naphthalenyl)cytidine, Cytidine, 2′-deoxy-N-(1,2,3,4-tetrahydro-2,3,4-trihydroxy-1-naphthalenyl)-, (1R-(1alpha,2beta,3beta,4alpha))-

Application

This compound is primarily used in nucleoside chemistry and medicinal research, particularly for investigating DNA adduct formation and repair mechanisms. Its tetrahydronaphthalene group enables studies on enzyme inhibition, such as targeting polymerases or nucleoside kinases. Researchers also explore its potential as a prodrug or antiviral/anticancer agent due to its modified nucleoside structure.

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