Description

Description

Methylmagnesium chloride (CAS No. 676-58-4) is a highly reactive Grignard reagent with the molecular formula CH₃ClMg. This organomagnesium compound is widely utilized in synthetic organic chemistry for nucleophilic addition reactions, serving as a methylating agent to form carbon-carbon bonds. Supplied as a solution in common solvents such as diethyl ether or tetrahydrofuran (THF), it is typically available in concentrations ranging from 1.0M to 3.0M. Methylmagnesium chloride must be handled under inert conditions (e.g., nitrogen or argon atmosphere) due to its extreme sensitivity to moisture and air. Ideal for laboratory-scale and industrial applications, this reagent is packaged in flame-sealed ampules or Sure/Seal? bottles to ensure stability and safety during storage and transport. Suitable for researchers and chemists working on advanced organic synthesis, pharmaceuticals, and specialty chemicals.

Application

Methylmagnesium chloride is primarily used as a strong nucleophile and base in organic synthesis, enabling the formation of new carbon-carbon bonds via Grignard reactions. It is commonly employed in the methylation of carbonyl compounds (e.g., ketones, aldehydes, esters) to produce tertiary alcohols. Additionally, it finds application in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. Due to its high reactivity, it is often used under anhydrous conditions with strict temperature control.

If you are interested or have any questions, please contact us at support@atomfair.com