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Atomfair Methyl 3-bromo-2-pyridinecarboxylate Methyl 3-Bromopicolinate C7H6BrNO2

Description Methyl 3-bromo-2-pyridinecarboxylate (CAS No. 53636-56-9) is a high-purity brominated pyridine derivative with the molecular formula C7H6BrNO2. This compound, also known as methyl 3-bromopicolinate, is a versatile building block in organic synthesis and pharmaceutical research. Its structure features a reactive bromine atom at the 3-position and an ester group at the 2-position of the pyridine ring, enabling diverse functionalization. Supplied as a crystalline solid with ??95% purity (HPLC), it is ideal for coupling reactions, heterocycle synthesis, and ligand preparation. Packaged under inert gas to ensure stability, this reagent is suitable for use in medicinal chemistry, agrochemical development, and material science…

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Description

Description

Methyl 3-bromo-2-pyridinecarboxylate (CAS No. 53636-56-9) is a high-purity brominated pyridine derivative with the molecular formula C7H6BrNO2. This compound, also known as methyl 3-bromopicolinate, is a versatile building block in organic synthesis and pharmaceutical research. Its structure features a reactive bromine atom at the 3-position and an ester group at the 2-position of the pyridine ring, enabling diverse functionalization. Supplied as a crystalline solid with ??95% purity (HPLC), it is ideal for coupling reactions, heterocycle synthesis, and ligand preparation. Packaged under inert gas to ensure stability, this reagent is suitable for use in medicinal chemistry, agrochemical development, and material science applications. Store in a cool, dry place away from light and moisture.

  • CAS No: 53636-56-9
  • Molecular Formula: C7H6BrNO2
  • Molecular Weight: 216.03
  • Exact Mass: 214.95819
  • Monoisotopic Mass: 214.95819
  • IUPAC Name: methyl 3-bromopyridine-2-carboxylate
  • SMILES: COC(=O)C1=C(C=CC=N1)Br
  • Synonyms: Methyl 3-bromo-2-pyridinecarboxylate, 814-519-2, Methyl 3-Bromopicolinate, 53636-56-9, Methyl 3-bromopyridine-2-carboxylate

Application

Methyl 3-bromo-2-pyridinecarboxylate serves as a key intermediate in Suzuki-Miyaura and Stille cross-coupling reactions for constructing biaryl systems. It is widely used in pharmaceutical research for the synthesis of kinase inhibitors and other nitrogen-containing heterocycles. The compound’s ester group allows further derivatization via hydrolysis or amidation, making it valuable for drug discovery pipelines.

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