Atomfair Imatinib amine C16H15N5

Description Imatinib amine (CAS No. 152460-10-1) is a high-purity pharmaceutical intermediate and key metabolite of Imatinib, a well-known tyrosine kinase inhibitor. With the molecular formula C16H15N5and IUPAC name 4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine , this compound is essential for research in medicinal chemistry and drug development. Imatinib amine is rigorously tested for quality, ensuring ??95% purity by HPLC, and is supplied as a lyophilized powder or in solution for precise experimental use. Ideal for researchers studying kinase inhibition pathways, metabolite profiling, and the synthesis of targeted cancer therapeutics. Store under inert conditions at -20??C to maintain stability.

Description

Description

Imatinib amine (CAS No. 152460-10-1) is a high-purity pharmaceutical intermediate and key metabolite of Imatinib, a well-known tyrosine kinase inhibitor. With the molecular formula C16H15N5 and IUPAC name 4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine, this compound is essential for research in medicinal chemistry and drug development. Imatinib amine is rigorously tested for quality, ensuring ??95% purity by HPLC, and is supplied as a lyophilized powder or in solution for precise experimental use. Ideal for researchers studying kinase inhibition pathways, metabolite profiling, and the synthesis of targeted cancer therapeutics. Store under inert conditions at -20??C to maintain stability.

  • CAS No: 152460-10-1
  • Molecular Formula: C16H15N5
  • Molecular Weight: 277.32
  • Exact Mass: 277.13274550
  • Monoisotopic Mass: 277.13274550
  • IUPAC Name: 4-methyl-3-N-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine
  • SMILES: CC1=C(C=C(C=C1)N)NC2=NC=CC(=N2)C3=CN=CC=C3
  • Synonyms: 152460-10-1, Imatinib amine, JR9RZF7KDS, Imatinib amine [USP], 1,3-Benzenediamine, 4-methyl-N3-(4-(3-pyridinyl)-2-pyrimidinyl)-

Application

Imatinib amine serves as a critical reference standard in pharmacokinetic studies of Imatinib, aiding in metabolite identification and quantification. It is widely used in oncology research to investigate the mechanisms of tyrosine kinase inhibition and resistance. This compound also supports the development of analytical methods for therapeutic drug monitoring in clinical settings.

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