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Atomfair Hydroxyflutamide C11H11F3N2O4

Description Hydroxyflutamide (CAS 52771-22-9) is a high-purity nonsteroidal antiandrogen compound with the molecular formula C11H11F3N2O4and IUPAC name 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide . This bioactive small molecule is the active metabolite of flutamide, exhibiting potent androgen receptor (AR) antagonism. Hydroxyflutamide is widely utilized in endocrinology and oncology research, particularly in studies involving prostate cancer and androgen-dependent pathways. Our product is rigorously tested by HPLC and NMR to ensure ??98% purity, meeting the stringent requirements of pharmaceutical and biochemical research applications. Supplied as a crystalline solid with batch-specific COA, it is ideal for in vitro and in vivo studies investigating hormonal regulation mechanisms.

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Description

Description

Hydroxyflutamide (CAS 52771-22-9) is a high-purity nonsteroidal antiandrogen compound with the molecular formula C11H11F3N2O4 and IUPAC name 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide. This bioactive small molecule is the active metabolite of flutamide, exhibiting potent androgen receptor (AR) antagonism. Hydroxyflutamide is widely utilized in endocrinology and oncology research, particularly in studies involving prostate cancer and androgen-dependent pathways. Our product is rigorously tested by HPLC and NMR to ensure ??98% purity, meeting the stringent requirements of pharmaceutical and biochemical research applications. Supplied as a crystalline solid with batch-specific COA, it is ideal for in vitro and in vivo studies investigating hormonal regulation mechanisms.

  • CAS No: 52771-22-9
  • Molecular Formula: C11H11F3N2O4
  • Molecular Weight: 292.21
  • Exact Mass: 292.06709132
  • Monoisotopic Mass: 292.06709132
  • IUPAC Name: 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
  • SMILES: CC(C)(C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F)O
  • Synonyms: Hydroxyflutamide, 2-hydroxyflutamide, Hydroxyniphtholide, hydroxy-flutamide, Sch 16423

Application

Hydroxyflutamide is primarily used as an androgen receptor antagonist in prostate cancer research, effectively blocking dihydrotestosterone (DHT) binding. It serves as a critical tool compound for studying androgen-dependent gene expression and cellular proliferation pathways. Researchers employ this molecule in xenograft models to investigate therapeutic responses in hormone-sensitive malignancies.

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