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Atomfair Diphenyl(pyrrolidin-2-yl)methanol Diphenylprolinol C17H19NO

Description Diphenyl(pyrrolidin-2-yl)methanol (CAS No. 112068-01-6) is a high-purity chiral compound with the molecular formula C17H19NO , widely utilized in asymmetric synthesis and pharmaceutical research. This white to off-white crystalline solid features a pyrrolidine ring substituted with a diphenylhydroxymethyl group, making it a valuable scaffold for chiral auxiliaries and ligands in catalysis. With a molecular weight of 253.34 g/mol, it exhibits excellent stability under standard laboratory conditions. Researchers rely on its enantiomeric purity for applications in stereoselective transformations, including aldol reactions and Michael additions. Available in >98% purity (HPLC), this compound is packaged under inert gas to ensure long-term integrity. Store…

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Description

Description

Diphenyl(pyrrolidin-2-yl)methanol (CAS No. 112068-01-6) is a high-purity chiral compound with the molecular formula C17H19NO, widely utilized in asymmetric synthesis and pharmaceutical research. This white to off-white crystalline solid features a pyrrolidine ring substituted with a diphenylhydroxymethyl group, making it a valuable scaffold for chiral auxiliaries and ligands in catalysis. With a molecular weight of 253.34 g/mol, it exhibits excellent stability under standard laboratory conditions. Researchers rely on its enantiomeric purity for applications in stereoselective transformations, including aldol reactions and Michael additions. Available in >98% purity (HPLC), this compound is packaged under inert gas to ensure long-term integrity. Store in a cool, dry place away from light and moisture for optimal performance.

  • CAS No: 112068-01-6
  • Molecular Formula: C17H19NO
  • Molecular Weight: 253.34
  • Exact Mass: 253.146664230
  • Monoisotopic Mass: 253.146664230
  • IUPAC Name: diphenyl(pyrrolidin-2-yl)methanol
  • SMILES: C1CC(NC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O
  • Synonyms: diphenyl(pyrrolidin-2-yl)methanol, Diphenylprolinol, 63401-04-7, alpha,alpha-diphenyl-2-pyrrolidinemethanol, (R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine

Application

Diphenyl(pyrrolidin-2-yl)methanol serves as a key chiral building block in asymmetric organocatalysis, particularly for enantioselective C-C bond formations. It demonstrates high efficacy as a ligand in metal-catalyzed reactions and as a precursor for proline-derived catalysts. The compound’s rigid structure enhances stereocontrol in synthetic routes to biologically active molecules, including APIs and natural product analogs. Researchers also employ it in the development of novel chiral stationary phases for chromatographic separations.

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