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Atomfair Cytosine arabinoside monophosphate C9H14N3O8P

Description Cytosine arabinoside monophosphate (CAS No. 63-37-6) is a nucleoside monophosphate analog with the molecular formula C9H14N3O8P . This biologically active compound is derived from cytosine arabinoside (Ara-C) and plays a critical role in biochemical and pharmacological research. As a phosphorylated derivative, it serves as a key intermediate in nucleotide metabolism and is widely studied for its potential therapeutic applications, particularly in oncology. The IUPAC name, [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate , reflects its precise structural configuration. Our high-purity product is rigorously tested for quality, ensuring optimal performance in research applications. Available in various quantities to suit laboratory needs.

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Description

Description

Cytosine arabinoside monophosphate (CAS No. 63-37-6) is a nucleoside monophosphate analog with the molecular formula C9H14N3O8P. This biologically active compound is derived from cytosine arabinoside (Ara-C) and plays a critical role in biochemical and pharmacological research. As a phosphorylated derivative, it serves as a key intermediate in nucleotide metabolism and is widely studied for its potential therapeutic applications, particularly in oncology. The IUPAC name, [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate, reflects its precise structural configuration. Our high-purity product is rigorously tested for quality, ensuring optimal performance in research applications. Available in various quantities to suit laboratory needs.

  • CAS No: 63-37-6
  • Molecular Formula: C9H14N3O8P
  • Molecular Weight: 323.20
  • Exact Mass: 323.05185141
  • Monoisotopic Mass: 323.05185141
  • IUPAC Name: [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
  • SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O
  • Synonyms: Cytosine arabinoside monophosphate, [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate, (5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl)methyl dihydrogen phosphate, 30811-80-4, NSC99445

Application

Cytosine arabinoside monophosphate is primarily used in cancer research as a metabolite of cytarabine (Ara-C), a chemotherapeutic agent for leukemia and lymphoma. It is studied for its role in DNA synthesis inhibition and its mechanism of action in targeting rapidly dividing cells. Researchers also utilize it to investigate nucleotide metabolism and resistance mechanisms in cancer therapeutics. Its phosphorylated form is essential for understanding intracellular activation pathways of nucleoside analogs.

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