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Atomfair Cytosar Cytarabine, Ara-C C9H13N3O5

Description Cytosar (CAS No. 69-74-9), also known as Cytarabine, is a pyrimidine nucleoside analog with the molecular formula C9H13N3O5. Its IUPAC name is 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one . This high-purity compound is widely utilized in biochemical and pharmaceutical research, particularly in oncology studies. Cytosar is a potent antimetabolite that interferes with DNA synthesis, making it a critical tool for investigating chemotherapy mechanisms. Available in lyophilized powder or solution form, it is rigorously tested for purity (??98% by HPLC) and stability to ensure reliable experimental results. Store at -20??C in a dry, dark environment to maintain efficacy.

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Description

Description

Cytosar (CAS No. 69-74-9), also known as Cytarabine, is a pyrimidine nucleoside analog with the molecular formula C9H13N3O5. Its IUPAC name is 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one. This high-purity compound is widely utilized in biochemical and pharmaceutical research, particularly in oncology studies. Cytosar is a potent antimetabolite that interferes with DNA synthesis, making it a critical tool for investigating chemotherapy mechanisms. Available in lyophilized powder or solution form, it is rigorously tested for purity (??98% by HPLC) and stability to ensure reliable experimental results. Store at -20??C in a dry, dark environment to maintain efficacy.

  • CAS No: 69-74-9
  • Molecular Formula: C9H13N3O5
  • Molecular Weight: 243.22
  • Exact Mass: 243.08552052
  • Monoisotopic Mass: 243.08552052
  • IUPAC Name: 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
  • Synonyms: Cytosar, 478511-21-6, [5′,5”-2H2]cytidine, 4-amino-1-pentofuranosylpyrimidin-2(1H)-one, .beta.-Arabinosylcytosine

Application

Cytosar is primarily used in cancer research as a chemotherapeutic agent, particularly for studying acute myeloid leukemia (AML) and other hematologic malignancies. It inhibits DNA polymerase by incorporating into DNA strands, leading to chain termination and apoptosis. Researchers also employ Cytosar to investigate drug resistance mechanisms and combination therapies in vitro and in vivo.

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