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Atomfair Cytosar Cytarabine, Ara-C C9H13N3O5

Description Cytosar (Cytarabine) is a pyrimidine nucleoside analog with the molecular formula C9H13N3O5and CAS number 65-46-3 . It is a potent chemotherapeutic agent widely used in research and clinical settings for its antineoplastic properties. Cytosar is structurally characterized as 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one , featuring a cytosine base linked to an arabinose sugar moiety. This compound is highly soluble in water and exhibits selective inhibition of DNA synthesis, making it invaluable for studying leukemia and lymphoma cell lines. Available in high-purity formulations, Cytosar is rigorously tested for stability, sterility, and consistency to meet the demands of pharmaceutical and biochemical research.

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Description

Description

Cytosar (Cytarabine) is a pyrimidine nucleoside analog with the molecular formula C9H13N3O5 and CAS number 65-46-3. It is a potent chemotherapeutic agent widely used in research and clinical settings for its antineoplastic properties. Cytosar is structurally characterized as 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one, featuring a cytosine base linked to an arabinose sugar moiety. This compound is highly soluble in water and exhibits selective inhibition of DNA synthesis, making it invaluable for studying leukemia and lymphoma cell lines. Available in high-purity formulations, Cytosar is rigorously tested for stability, sterility, and consistency to meet the demands of pharmaceutical and biochemical research.

  • CAS No: 65-46-3
  • Molecular Formula: C9H13N3O5
  • Molecular Weight: 243.22
  • Exact Mass: 243.08552052
  • Monoisotopic Mass: 243.08552052
  • IUPAC Name: 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
  • Synonyms: Cytosar, 478511-21-6, [5′,5”-2H2]cytidine, 4-amino-1-pentofuranosylpyrimidin-2(1H)-one, .beta.-Arabinosylcytosine

Application

Cytosar is primarily utilized as an antimetabolite in chemotherapy, specifically targeting acute myeloid leukemia (AML) and other hematologic malignancies. It functions by inhibiting DNA polymerase, thereby disrupting DNA replication and inducing apoptosis in rapidly dividing cancer cells. Researchers also employ Cytosar in in vitro studies to investigate mechanisms of drug resistance and synergistic effects with other anticancer agents.

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