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Atomfair Carbamoylpyridoxal 5′-phosphate CPLP C9H11N2O7P

Description Carbamoylpyridoxal 5′-phosphate (CPLP) is a biologically active phosphorylated derivative of pyridoxal, featuring a carbamoyl group at the 4′-position. With the molecular formula C9H11N2O7P and CAS number 1341216-35-0 , this compound serves as a critical cofactor in enzymatic reactions, particularly those involving vitamin B6metabolism. Its IUPAC name, (4-hydroxy-8-methyl-2-oxo-3,4-dihydropyrido[4,3-e][1,3]oxazin-5-yl)methyl dihydrogen phosphate , reflects its intricate heterocyclic structure. CPLP is highly soluble in aqueous buffers and exhibits stability under controlled conditions, making it suitable for biochemical and pharmaceutical research. Available in high-purity grades (>95%), it is ideal for studies on transamination, decarboxylation, and racemization reactions.

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Description

Description

Carbamoylpyridoxal 5′-phosphate (CPLP) is a biologically active phosphorylated derivative of pyridoxal, featuring a carbamoyl group at the 4′-position. With the molecular formula C9H11N2O7P and CAS number 1341216-35-0, this compound serves as a critical cofactor in enzymatic reactions, particularly those involving vitamin B6 metabolism. Its IUPAC name, (4-hydroxy-8-methyl-2-oxo-3,4-dihydropyrido[4,3-e][1,3]oxazin-5-yl)methyl dihydrogen phosphate, reflects its intricate heterocyclic structure. CPLP is highly soluble in aqueous buffers and exhibits stability under controlled conditions, making it suitable for biochemical and pharmaceutical research. Available in high-purity grades (>95%), it is ideal for studies on transamination, decarboxylation, and racemization reactions.

  • CAS No: 1341216-35-0
  • Molecular Formula: C9H11N2O7P
  • Molecular Weight: 290.17
  • Exact Mass: 290.03038769
  • Monoisotopic Mass: 290.03038769
  • IUPAC Name: (4-hydroxy-8-methyl-2-oxo-3,4-dihydropyrido[4,3-e][1,3]oxazin-5-yl)methyl dihydrogen phosphate
  • SMILES: CC1=NC=C(C2=C1OC(=O)NC2O)COP(=O)(O)O
  • Synonyms: Carbamoylpyridoxal 5′-phosphate, 134121-41-8, 4′-Carbamoylpyridoxal 5′-phosphate, 2H-Pyrido(4,3-e)-1,3-oxazin-2-one, 3,4-dihydro-4-hydroxy-8-methyl-5-((phosphonooxy)methyl)-, CPLP

Application

Carbamoylpyridoxal 5′-phosphate (CPLP) is widely used as a coenzyme in research on vitamin B6-dependent enzymes, facilitating studies on reaction mechanisms and enzyme kinetics. It plays a key role in modeling metabolic pathways involving amino acid biosynthesis and degradation. Researchers also employ CPLP as a precursor for synthesizing analogs to probe active sites of pyridoxal phosphate-dependent enzymes.

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