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Atomfair Bis(2-isothiocyanatophenyl) sulfone C14H8N2O2S3

Description Bis(2-isothiocyanatophenyl) sulfone (CAS No. 452-70-0) is a high-purity sulfone-based compound with the molecular formula C14H8N2O2S3, widely utilized in organic synthesis and pharmaceutical research. This reagent features two reactive isothiocyanate groups, making it a versatile building block for crosslinking applications, conjugation chemistry, and the development of heterocyclic compounds. Its IUPAC name, 1-isothiocyanato-2-(2-isothiocyanatophenyl)sulfonylbenzene , reflects its symmetrical structure, which enhances stability and reactivity in nucleophilic substitution reactions. Ideal for researchers in medicinal chemistry and materials science, this product is rigorously tested for purity (typically ??95% by HPLC) and is supplied in sealed packaging under inert conditions to ensure long-term stability. Synonyms…

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Description

Description

Bis(2-isothiocyanatophenyl) sulfone (CAS No. 452-70-0) is a high-purity sulfone-based compound with the molecular formula C14H8N2O2S3, widely utilized in organic synthesis and pharmaceutical research. This reagent features two reactive isothiocyanate groups, making it a versatile building block for crosslinking applications, conjugation chemistry, and the development of heterocyclic compounds. Its IUPAC name, 1-isothiocyanato-2-(2-isothiocyanatophenyl)sulfonylbenzene, reflects its symmetrical structure, which enhances stability and reactivity in nucleophilic substitution reactions. Ideal for researchers in medicinal chemistry and materials science, this product is rigorously tested for purity (typically ??95% by HPLC) and is supplied in sealed packaging under inert conditions to ensure long-term stability. Synonyms include NSC142074 and DTXSID30301254.

  • CAS No: 452-70-0
  • Molecular Formula: C14H8N2O2S3
  • Molecular Weight: 332.4
  • Exact Mass: 331.97479102
  • Monoisotopic Mass: 331.97479102
  • IUPAC Name: 1-isothiocyanato-2-(2-isothiocyanatophenyl)sulfonylbenzene
  • SMILES: C1=CC=C(C(=C1)N=C=S)S(=O)(=O)C2=CC=CC=C2N=C=S
  • Synonyms: 40939-91-1, bis(2-isothiocyanatophenyl) sulfone, NSC142074, SCHEMBL11117613, DTXSID30301254

Application

Bis(2-isothiocyanatophenyl) sulfone is primarily employed as a bifunctional linker in peptide synthesis and protein modification due to its reactive isothiocyanate groups. It serves as a key intermediate in the preparation of sulfonamide-based polymers and dyes, offering thermal and chemical resistance. Researchers also utilize it in crosslinking studies for biomaterials and as a precursor for bioactive heterocycles in drug discovery.

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