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Atomfair Binol BINOL C20H14O2
Description Binol (1,1′-Bi-2-naphthol) is a chiral bidentate ligand and auxiliary widely used in asymmetric synthesis and catalysis. With the molecular formula C20H14O2and CAS number 18531-99-2 , this binaphthyl compound features two hydroxyl groups at the 2- and 2′-positions, enabling its utility in coordinating metal centers for enantioselective transformations. Its rigid, axially chiral structure makes it invaluable in asymmetric hydrogenation, coupling reactions, and organocatalysis. Available in high purity grades, Binol is a critical reagent for researchers developing novel catalytic systems or stereoselective methodologies. Proper storage under inert conditions is recommended to preserve its reactivity.
Description
Description
Binol (1,1′-Bi-2-naphthol) is a chiral bidentate ligand and auxiliary widely used in asymmetric synthesis and catalysis. With the molecular formula C20H14O2 and CAS number 18531-99-2, this binaphthyl compound features two hydroxyl groups at the 2- and 2′-positions, enabling its utility in coordinating metal centers for enantioselective transformations. Its rigid, axially chiral structure makes it invaluable in asymmetric hydrogenation, coupling reactions, and organocatalysis. Available in high purity grades, Binol is a critical reagent for researchers developing novel catalytic systems or stereoselective methodologies. Proper storage under inert conditions is recommended to preserve its reactivity.
- CAS No: 18531-99-2
- Molecular Formula: C20H14O2
- Molecular Weight: 286.3
- Exact Mass: 286.099379685
- Monoisotopic Mass: 286.099379685
- IUPAC Name: 1-(2-hydroxynaphthalen-1-yl)naphthalen-2-ol
- SMILES: C1=CC=C2C(=C1)C=CC(=C2C3=C(C=CC4=CC=CC=C43)O)O
- Synonyms: 1,1′-Bi-2-naphthol, 602-09-5, (S)-(-)-1,1′-Bi-2-naphthol, [1,1′-Binaphthalene]-2,2′-diol, binol
Application
Binol serves as a versatile chiral ligand in asymmetric catalysis, particularly in enantioselective C-C bond-forming reactions. It is widely employed in the synthesis of pharmaceuticals and fine chemicals due to its ability to induce high stereoselectivity. Researchers utilize Binol-derived catalysts for asymmetric oxidations, reductions, and cycloadditions. Its derivatives are also pivotal in materials science for constructing chiral frameworks.
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