Description

Description

2-(2-Fluorophenyl)acetonitrile (CAS No. 326-62-5) is a high-purity fluorinated organic compound with the molecular formula C₈H₆FN. This aromatic nitrile derivative features a fluorine substituent at the ortho position of the phenyl ring, enhancing its reactivity and utility in synthetic chemistry applications. The compound is supplied as a clear to pale-yellow liquid with a characteristic aromatic odor, suitable for use in research, pharmaceutical intermediates, and fine chemical synthesis. Its high chemical stability and compatibility with various reaction conditions make it a valuable building block for the preparation of fluorinated heterocycles, agrochemicals, and bioactive molecules. Store in a cool, dry place under inert conditions to ensure prolonged shelf life.

Application

2-(2-Fluorophenyl)acetonitrile is widely employed as a key intermediate in the synthesis of fluorinated pharmaceuticals, including CNS-active compounds and enzyme inhibitors. Its reactivity as a nitrile precursor enables its use in the preparation of carboxylic acids, amides, and heterocyclic scaffolds via hydrolysis or cyclization reactions. Researchers also utilize this compound in the development of agrochemicals and specialty materials requiring fluorinated aromatic motifs.

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