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Atomfair Ancitabine hydrochloride C9H12ClN3O4

Description Ancitabine hydrochloride (CAS No. 10212-25-6) is a nucleoside analogue with the molecular formula C9H12ClN3O4. This compound, also known as Cyclocytidine hydrochloride, is a white to off-white crystalline powder with high purity, suitable for research and pharmaceutical applications. Its IUPAC name is (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol;hydrochloride. Ancitabine hydrochloride is a stabilized derivative of cytarabine, designed to enhance metabolic stability and prolong therapeutic effects. It is widely utilized in biochemical and oncology research due to its role as an antimetabolite and potential chemotherapeutic agent. The product is supplied with comprehensive analytical data, including HPLC purity, NMR, and MSDS, ensuring consistency and reliability for laboratory…

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Description

Description

Ancitabine hydrochloride (CAS No. 10212-25-6) is a nucleoside analogue with the molecular formula C9H12ClN3O4. This compound, also known as Cyclocytidine hydrochloride, is a white to off-white crystalline powder with high purity, suitable for research and pharmaceutical applications. Its IUPAC name is (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol;hydrochloride. Ancitabine hydrochloride is a stabilized derivative of cytarabine, designed to enhance metabolic stability and prolong therapeutic effects. It is widely utilized in biochemical and oncology research due to its role as an antimetabolite and potential chemotherapeutic agent. The product is supplied with comprehensive analytical data, including HPLC purity, NMR, and MSDS, ensuring consistency and reliability for laboratory use.

  • CAS No: 10212-25-6
  • Molecular Formula: C9H12ClN3O4
  • Molecular Weight: 261.66
  • Exact Mass: 261.0516336
  • Monoisotopic Mass: 261.0516336
  • IUPAC Name: (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol;hydrochloride
  • SMILES: C1=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)OC2=NC1=N.Cl
  • Synonyms: Cyclocytidine hydrochloride, ANCITABINE HYDROCHLORIDE, (-)-Cyclocytidine hydrochloride, OCTD hydrochloride, 2,2′-O-Cyclocytidine hydrochloride

Application

Ancitabine hydrochloride is primarily used in cancer research as a cytostatic agent, inhibiting DNA synthesis in rapidly dividing cells. It has shown promise in studies related to leukemia and other hematologic malignancies due to its mechanism of action as a nucleoside analogue. Researchers also employ it to investigate drug resistance mechanisms and combination therapies in oncology. Its stabilized structure makes it a valuable tool for prolonged in vitro and in vivo studies.

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