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Atomfair alpha-Methyl-DL-tryptophan C12H14N2O2

Description ??-Methyl-DL-tryptophan (CAS: 16709-25-4) is a synthetic tryptophan derivative with the molecular formula C12H14N2O2and IUPAC name 2-amino-3-(1H-indol-3-yl)-2-methylpropanoic acid . This racemic mixture is a valuable chiral building block in organic synthesis and pharmaceutical research. As a modified amino acid, it features a methyl group at the alpha position, altering its metabolic pathway compared to natural tryptophan. The compound is provided as a high-purity solid (>98%) with comprehensive analytical characterization including HPLC, NMR, and MS data. Suitable for use as a reference standard, metabolic inhibitor, or precursor in medicinal chemistry applications. Packaged under inert gas in amber glass vials to ensure…

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Description

Description

??-Methyl-DL-tryptophan (CAS: 16709-25-4) is a synthetic tryptophan derivative with the molecular formula C12H14N2O2 and IUPAC name 2-amino-3-(1H-indol-3-yl)-2-methylpropanoic acid. This racemic mixture is a valuable chiral building block in organic synthesis and pharmaceutical research. As a modified amino acid, it features a methyl group at the alpha position, altering its metabolic pathway compared to natural tryptophan. The compound is provided as a high-purity solid (>98%) with comprehensive analytical characterization including HPLC, NMR, and MS data. Suitable for use as a reference standard, metabolic inhibitor, or precursor in medicinal chemistry applications. Packaged under inert gas in amber glass vials to ensure stability.

  • CAS No: 16709-25-4
  • Molecular Formula: C12H14N2O2
  • Molecular Weight: 218.25
  • Exact Mass: 218.105527694
  • Monoisotopic Mass: 218.105527694
  • IUPAC Name: 2-amino-3-(1H-indol-3-yl)-2-methylpropanoic acid
  • SMILES: CC(CC1=CNC2=CC=CC=C21)(C(=O)O)N
  • Synonyms: alpha-Methyl-DL-tryptophan, 153-91-3, 2-amino-3-(1H-indol-3-yl)-2-methylpropanoic acid, DL-alpha-Methyltryptophan, alpha-methyl-D,L-tryptophan

Application

??-Methyl-DL-tryptophan serves as a key intermediate in neuroscience research, particularly in studies of serotonin synthesis inhibition. The methyl modification makes it resistant to decarboxylation, allowing investigation of tryptophan metabolism pathways. Researchers utilize this compound in PET radiotracer development for tumor imaging due to altered amino acid uptake in cancer cells. It also finds application as a non-natural amino acid in peptide modification studies and enzyme substrate investigations.

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