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Atomfair Adenosine 5′,3′-phosphouridine (3′-5′)UpA C19H24N7O12P
Description Adenosine 5′,3′-phosphouridine (CAS 327-74-2) is a high-purity nucleotide derivative with the molecular formula C19H24N7O12P , widely utilized in biochemical and pharmaceutical research. This compound, also known as Uridylyladenosine , serves as a critical intermediate in nucleic acid synthesis and enzymatic studies. Its IUPAC name, [5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate , reflects its intricate structure, combining adenosine and uridine moieties linked by a phosphodiester bond. Ideal for researchers studying RNA metabolism, ligation reactions, and nucleotide modifications, this product is rigorously tested for purity and stability. Available in lyophilized or solution form, it is suitable for HPLC, mass spectrometry, and enzymatic assays…
Description
Description
Adenosine 5′,3′-phosphouridine (CAS 327-74-2) is a high-purity nucleotide derivative with the molecular formula C19H24N7O12P, widely utilized in biochemical and pharmaceutical research. This compound, also known as Uridylyladenosine, serves as a critical intermediate in nucleic acid synthesis and enzymatic studies. Its IUPAC name, [5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate, reflects its intricate structure, combining adenosine and uridine moieties linked by a phosphodiester bond. Ideal for researchers studying RNA metabolism, ligation reactions, and nucleotide modifications, this product is rigorously tested for purity and stability. Available in lyophilized or solution form, it is suitable for HPLC, mass spectrometry, and enzymatic assays. Store at -20??C in a dry environment to ensure prolonged shelf life.
- CAS No: 327-74-2
- Molecular Formula: C19H24N7O12P
- Molecular Weight: 573.4
- Exact Mass: 573.12205622
- Monoisotopic Mass: 573.12205622
- IUPAC Name: [5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate
- SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O
- Synonyms: Uridylyladenosine, (3′,5′)-Uridylyladenosine, Adenosine 5′,3′-phosphouridine, Uridine-3′,5′-adenosine phosphate, (3′-5′)UpA
Application
Adenosine 5′,3′-phosphouridine is extensively used in RNA biochemistry to investigate nucleotide-nucleotide interactions and enzymatic ligation mechanisms. Researchers employ it as a substrate for RNA ligases and nucleotidyltransferases to study repair and splicing pathways. Its role in structural biology aids in probing RNA-protein binding dynamics, while its modified backbone supports therapeutic oligonucleotide development.
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