Description

Description

8-Bromoquinoline-4-carboxylic acid (CAS No. 121490-67-3) is a high-purity brominated quinoline derivative with the molecular formula C₁₀H₆BrNO₂. This compound is a versatile building block in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. Its unique structure, featuring a bromine substituent at the 8-position and a carboxylic acid group at the 4-position of the quinoline ring, enables selective functionalization for complex molecule construction. Ideal for researchers in medicinal chemistry, this product is rigorously tested for quality and supplied with comprehensive analytical data (including ¹H NMR, ¹³C NMR, and HPLC) to ensure reproducibility in your experiments. Store in a cool, dry place under inert conditions to maintain stability.

Application

8-Bromoquinoline-4-carboxylic acid serves as a key intermediate in the synthesis of quinoline-based drug candidates, particularly in antimicrobial and anticancer research. Its reactive bromine and carboxyl groups allow for cross-coupling reactions (e.g., Suzuki-Miyaura) and amide bond formation, respectively. This compound is also employed in material science for developing fluorescent probes and coordination complexes with transition metals. Researchers value it for constructing heterocyclic frameworks in high-throughput screening libraries.

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