Atomfair

Awaiting product image

Atomfair 7-Iodo-7-deaza-D-guanosine C11H13IN4O4

Description 7-Iodo-7-deaza-D-guanosine (CAS: 24386-93-4) is a modified nucleoside analog with the molecular formula C11H13IN4O4. This compound, also known by its IUPAC name 2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol, is a valuable building block in nucleic acid chemistry and biochemical research. The iodine substitution at the 7-position of the deazaguanosine scaffold enhances its utility in cross-coupling reactions, making it ideal for synthesizing labeled probes or modified oligonucleotides. With a purity grade suitable for research applications, this product is supplied as a lyophilized solid and should be stored at -20??C under inert conditions to ensure stability. Researchers can rely on its consistent quality for studies involving nucleoside…

Category:
Brands:

Description

Description

7-Iodo-7-deaza-D-guanosine (CAS: 24386-93-4) is a modified nucleoside analog with the molecular formula C11H13IN4O4. This compound, also known by its IUPAC name 2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol, is a valuable building block in nucleic acid chemistry and biochemical research. The iodine substitution at the 7-position of the deazaguanosine scaffold enhances its utility in cross-coupling reactions, making it ideal for synthesizing labeled probes or modified oligonucleotides. With a purity grade suitable for research applications, this product is supplied as a lyophilized solid and should be stored at -20??C under inert conditions to ensure stability. Researchers can rely on its consistent quality for studies involving nucleoside metabolism, antiviral drug development, and structural biology.

  • CAS No: 24386-93-4
  • Molecular Formula: C11H13IN4O4
  • Molecular Weight: 392.15
  • Exact Mass: 391.99815
  • Monoisotopic Mass: 391.99815
  • IUPAC Name: 2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
  • SMILES: C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)I
  • Synonyms: 7-Iodo-7-deaza-D-guanosine, 444020-71-7, (2S,3S,4R,5S)-2-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, BiomolKI_000049, BiomolKI2_000055

Application

7-Iodo-7-deaza-D-guanosine is primarily used in nucleic acid research as a precursor for modified nucleosides and oligonucleotides. Its iodine moiety facilitates site-specific modifications via palladium-catalyzed cross-coupling reactions, enabling the synthesis of fluorescent or biotin-labeled probes. This compound is also investigated for its potential antiviral properties due to its ability to mimic natural nucleosides and interfere with viral replication. Additionally, it serves as a valuable tool in structural studies of nucleic acid-protein interactions.

If you are interested or have any questions, please contact us at support@atomfair.com