Atomfair

Awaiting product image

Atomfair 6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile C12H7FN2O

Description 6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS No. 588729-99-1) is a high-purity fluorinated pyridine derivative with the molecular formula C12H7FN2O. This compound is a valuable heterocyclic building block for pharmaceutical and agrochemical research, featuring a reactive cyano group and a keto functionality at the 2-position of the pyridine ring. The 4-fluorophenyl substitution enhances its potential as a scaffold for drug discovery, particularly in kinase inhibition and CNS-targeted therapeutics. With a molecular weight of 214.20 g/mol, this crystalline solid is supplied with comprehensive analytical data including HPLC purity (>98%),1H/13C NMR, and mass spectrometry verification. Proper storage at 2-8??C under inert atmosphere ensures long-term stability of…

Category:
Brands:

Description

Description

6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS No. 588729-99-1) is a high-purity fluorinated pyridine derivative with the molecular formula C12H7FN2O. This compound is a valuable heterocyclic building block for pharmaceutical and agrochemical research, featuring a reactive cyano group and a keto functionality at the 2-position of the pyridine ring. The 4-fluorophenyl substitution enhances its potential as a scaffold for drug discovery, particularly in kinase inhibition and CNS-targeted therapeutics. With a molecular weight of 214.20 g/mol, this crystalline solid is supplied with comprehensive analytical data including HPLC purity (>98%), 1H/13C NMR, and mass spectrometry verification. Proper storage at 2-8??C under inert atmosphere ensures long-term stability of this light-sensitive compound. Available in research quantities from 100mg to 10g with custom synthesis options.

  • CAS No: 588729-99-1
  • Molecular Formula: C12H7FN2O
  • Molecular Weight: 214.19
  • Exact Mass: 214.05424101
  • Monoisotopic Mass: 214.05424101
  • IUPAC Name: 6-(4-fluorophenyl)-2-oxo-1H-pyridine-3-carbonitrile
  • SMILES: C1=CC(=CC=C1C2=CC=C(C(=O)N2)C#N)F
  • Synonyms: 31755-80-3, 6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile, DTXSID40377546, DTXCID00328574, 6-(4-fluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

Application

This fluorinated pyridine-carbonitrile derivative serves as a key intermediate in medicinal chemistry for developing kinase inhibitors and neurotransmitter modulators. Researchers utilize its reactive sites for palladium-catalyzed cross-coupling reactions to create diverse pharmacophores. The compound shows particular promise in structure-activity relationship studies for CNS disorders due to its ability to cross the blood-brain barrier. Its electron-withdrawing groups make it suitable for designing electron-deficient heterocyclic systems in material science applications.

If you are interested or have any questions, please contact us at support@atomfair.com