Atomfair

Awaiting product image

Atomfair 5-Fluorouracil arabinoside C9H11FN2O6

Description 5-Fluorouracil arabinoside (CAS No. 316-46-1) is a fluorinated nucleoside analog with the molecular formula C9H11FN2O6. This compound, also known by its IUPAC name 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione , is a derivative of uracil where a fluorine atom replaces hydrogen at the 5-position, conjugated to an arabinose sugar moiety. It is a white to off-white crystalline powder, soluble in water and polar organic solvents, and is highly stable under recommended storage conditions (2-8??C in a dry environment). 5-Fluorouracil arabinoside is a critical intermediate in biochemical and pharmaceutical research, particularly in the study of antimetabolite therapies and nucleoside-based drug development. Its high purity (>98%)…

Category:
Brands:

Description

Description

5-Fluorouracil arabinoside (CAS No. 316-46-1) is a fluorinated nucleoside analog with the molecular formula C9H11FN2O6. This compound, also known by its IUPAC name 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione, is a derivative of uracil where a fluorine atom replaces hydrogen at the 5-position, conjugated to an arabinose sugar moiety. It is a white to off-white crystalline powder, soluble in water and polar organic solvents, and is highly stable under recommended storage conditions (2-8??C in a dry environment).

5-Fluorouracil arabinoside is a critical intermediate in biochemical and pharmaceutical research, particularly in the study of antimetabolite therapies and nucleoside-based drug development. Its high purity (>98%) makes it suitable for in vitro and in vivo studies, including cytotoxicity assays, enzyme inhibition research, and metabolic pathway analysis. This product is rigorously tested via HPLC, NMR, and mass spectrometry to ensure consistency and reliability for scientific applications.

  • CAS No: 316-46-1
  • Molecular Formula: C9H11FN2O6
  • Molecular Weight: 262.19
  • Exact Mass: 262.06011424
  • Monoisotopic Mass: 262.06011424
  • IUPAC Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione
  • SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)F
  • Synonyms: 5-Fluorouracil arabinoside, 18814-21-6, 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-pyrimidine-2,4-dione, 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione, MLS002702026

Application

5-Fluorouracil arabinoside is primarily used in oncology research as a precursor for studying fluoropyrimidine-based chemotherapeutic agents. It serves as a model compound for investigating mechanisms of action in antimetabolite drugs targeting DNA/RNA synthesis. Researchers also utilize it in metabolic studies to understand the pharmacokinetics of fluorinated nucleosides. Its role in enzyme inhibition assays, particularly thymidylate synthase, makes it valuable for drug discovery pipelines.

If you are interested or have any questions, please contact us at support@atomfair.com