Description

Description

5-Fluoro-3-methylisobenzofuran-1(3H)-one (CAS No. 1803573-19-4) is a high-purity fluorinated isobenzofuranone derivative with the molecular formula C₉H₇FO₂. This compound, also known by its IUPAC name 5-fluoro-3-methyl-3H-2-benzofuran-1-one, is a valuable building block in organic synthesis and pharmaceutical research. Its unique structure, featuring a fluorine substituent at the 5-position and a methyl group at the 3-position of the isobenzofuranone core, makes it an ideal intermediate for the development of novel bioactive molecules. Our product is rigorously quality-controlled to ensure ??95% purity (HPLC) and is supplied as a white to off-white crystalline solid. It is packaged under inert conditions to guarantee stability and longevity. Researchers can utilize this compound in the synthesis of fluorinated heterocycles, drug candidates, and agrochemicals, where its electron-withdrawing fluorine atom may enhance metabolic stability and binding affinity.

Application

5-Fluoro-3-methylisobenzofuran-1(3H)-one serves as a versatile intermediate in medicinal chemistry for the synthesis of fluorinated drug candidates, particularly in CNS and oncology research. Its isobenzofuranone scaffold is useful for constructing protease inhibitors and kinase modulators. The compound’s fluorine atom improves pharmacokinetic properties, making it valuable in lead optimization. Additionally, it finds application in materials science as a precursor for fluorinated polymers with enhanced thermal stability.

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