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Atomfair 5-Chloro-2-fluorotoluene C7H6ClF

Description 5-Chloro-2-fluorotoluene (CAS No. 452-66-4) is a high-purity halogenated aromatic compound with the molecular formula C7H6ClF and IUPAC name 4-chloro-1-fluoro-2-methylbenzene . This specialty chemical is a valuable intermediate in organic synthesis, characterized by its clear to pale-yellow liquid appearance and distinct aromatic properties. With a molecular weight of 144.57 g/mol, it offers excellent reactivity for electrophilic substitution and cross-coupling reactions. Our product is rigorously tested to meet >98% purity standards (GC) and is supplied in sealed, light-resistant containers under inert gas to ensure stability. Ideal for pharmaceutical, agrochemical, and material science research, this compound is a key building block for…

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Description

Description

5-Chloro-2-fluorotoluene (CAS No. 452-66-4) is a high-purity halogenated aromatic compound with the molecular formula C7H6ClF and IUPAC name 4-chloro-1-fluoro-2-methylbenzene. This specialty chemical is a valuable intermediate in organic synthesis, characterized by its clear to pale-yellow liquid appearance and distinct aromatic properties. With a molecular weight of 144.57 g/mol, it offers excellent reactivity for electrophilic substitution and cross-coupling reactions. Our product is rigorously tested to meet >98% purity standards (GC) and is supplied in sealed, light-resistant containers under inert gas to ensure stability. Ideal for pharmaceutical, agrochemical, and material science research, this compound is a key building block for fluorinated derivatives and fine chemical synthesis.

  • CAS No: 452-66-4
  • Molecular Formula: C7H6ClF
  • Molecular Weight: 144.57
  • Exact Mass: 144.0142060
  • Monoisotopic Mass: 144.0142060
  • IUPAC Name: 4-chloro-1-fluoro-2-methylbenzene
  • SMILES: CC1=C(C=CC(=C1)Cl)F
  • Synonyms: 5-Chloro-2-fluorotoluene, 452-66-4, 4-chloro-1-fluoro-2-methylbenzene, Benzene, 4-chloro-1-fluoro-2-methyl-, AI3-52646

Application

5-Chloro-2-fluorotoluene serves as a versatile precursor in the synthesis of fluorinated pharmaceuticals and liquid crystal materials. It is particularly valuable in Suzuki-Miyaura coupling reactions to create biaryl structures for drug discovery. The compound’s chlorine and fluorine substituents enable selective functionalization in agrochemical active ingredient development. Researchers also utilize it to engineer advanced polymers with tailored electronic properties.

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