Atomfair

Awaiting product image

Atomfair 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol 6-Hydroxypyridine-3-boronic acid pinacol ester C11H16BNO3

Description 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol (CAS: 1054483-78-1) is a high-purity boronic ester derivative with the molecular formula C11H16BNO3. This compound features a pinacol-protected boronic acid group attached to a pyridin-2-ol scaffold, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions and other transition-metal-catalyzed processes. Its stability under ambient conditions and compatibility with diverse reaction conditions make it ideal for pharmaceutical, agrochemical, and materials science research. The product is supplied as a white to off-white crystalline solid with ??95% purity (HPLC), ensuring reliable performance in synthetic applications. Proper storage under inert atmosphere at 2-8??C is recommended to maintain stability.

Category:
Brands:

Description

Description

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol (CAS: 1054483-78-1) is a high-purity boronic ester derivative with the molecular formula C11H16BNO3. This compound features a pinacol-protected boronic acid group attached to a pyridin-2-ol scaffold, making it a versatile intermediate for Suzuki-Miyaura cross-coupling reactions and other transition-metal-catalyzed processes. Its stability under ambient conditions and compatibility with diverse reaction conditions make it ideal for pharmaceutical, agrochemical, and materials science research. The product is supplied as a white to off-white crystalline solid with ??95% purity (HPLC), ensuring reliable performance in synthetic applications. Proper storage under inert atmosphere at 2-8??C is recommended to maintain stability.

  • CAS No: 1054483-78-1
  • Molecular Formula: C11H16BNO3
  • Molecular Weight: 221.06
  • Exact Mass: 221.1223235
  • Monoisotopic Mass: 221.1223235
  • IUPAC Name: 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyridin-2-one
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CNC(=O)C=C2
  • Synonyms: 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol, 690-572-3, 1054483-78-1, 6-HYDROXYPYRIDINE-3-BORONIC ACID PINACOL ESTER, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyridin-2-one

Application

This compound serves as a key building block in the synthesis of biaryl structures via Suzuki-Miyaura coupling, particularly for introducing pyridin-2-ol moieties into complex molecules. It finds application in the development of pharmaceutical candidates, especially kinase inhibitors and receptor modulators. Researchers also utilize it in material science for creating boron-doped organic electronic materials. The pinacol ester group enhances stability while remaining reactive under standard cross-coupling conditions.

If you are interested or have any questions, please contact us at support@atomfair.com