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Atomfair 4,5-Dichloro-6-methyl-2-(pyridin-2-yl)pyrimidine C10H7Cl2N3

Description 4,5-Dichloro-6-methyl-2-(pyridin-2-yl)pyrimidine (CAS No. 121177-82-0) is a high-purity heterocyclic compound with the molecular formula C10H7Cl2N3. This pyrimidine derivative features a dichloro-methyl substitution pattern at the 4,5,6-positions and a pyridinyl moiety at the 2-position, making it a versatile intermediate for pharmaceutical and agrochemical synthesis. With a molecular weight of 228.09 g/mol , this compound is supplied as a crystalline solid with ??95% purity (HPLC). Ideal for medicinal chemistry applications, it serves as a key scaffold in the development of kinase inhibitors and other biologically active molecules. Proper storage at 2-8??C under inert conditions is recommended to ensure stability.

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Description

Description

4,5-Dichloro-6-methyl-2-(pyridin-2-yl)pyrimidine (CAS No. 121177-82-0) is a high-purity heterocyclic compound with the molecular formula C10H7Cl2N3. This pyrimidine derivative features a dichloro-methyl substitution pattern at the 4,5,6-positions and a pyridinyl moiety at the 2-position, making it a versatile intermediate for pharmaceutical and agrochemical synthesis. With a molecular weight of 228.09 g/mol, this compound is supplied as a crystalline solid with ??95% purity (HPLC). Ideal for medicinal chemistry applications, it serves as a key scaffold in the development of kinase inhibitors and other biologically active molecules. Proper storage at 2-8??C under inert conditions is recommended to ensure stability.

  • CAS No: 121177-82-0
  • Molecular Formula: C10H7Cl2N3
  • Molecular Weight: 240.09
  • Exact Mass: 239.0017026
  • Monoisotopic Mass: 239.0017026
  • IUPAC Name: 4,5-dichloro-6-methyl-2-pyridin-2-ylpyrimidine
  • SMILES: CC1=C(C(=NC(=N1)C2=CC=CC=N2)Cl)Cl
  • Synonyms: 306935-55-7, 4,5-dichloro-6-methyl-2-(pyridin-2-yl)pyrimidine, DTXSID40371084, DTXCID00322118, 4,5-Dichloro-6-methyl-2-(2-pyridyl)pyrimidine

Application

4,5-Dichloro-6-methyl-2-(pyridin-2-yl)pyrimidine is primarily used as a building block in the synthesis of small-molecule therapeutics, particularly kinase inhibitors. Its dichloro-pyrimidine core enables selective functionalization for structure-activity relationship (SAR) studies. Researchers also employ it in cross-coupling reactions to create novel heterocyclic libraries for high-throughput screening. The compound’s pyridinyl group enhances binding affinity to biological targets, making it valuable in drug discovery pipelines.

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