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Atomfair 4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane C10H15BO2S

Description 4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane (CAS No. 193978-23-3) is a high-purity boronic ester derivative with the molecular formula C10H15BO2S. This compound features a thiophene-substituted dioxaborolane structure, making it a valuable intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its robust stability and reactivity under mild conditions make it ideal for constructing complex heterocyclic frameworks. The product is supplied as a crystalline solid with ??95% purity (HPLC), ensuring consistent performance in research and industrial applications. Proper storage under inert conditions (argon or nitrogen) is recommended to maintain its integrity.

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Description

Description

4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane (CAS No. 193978-23-3) is a high-purity boronic ester derivative with the molecular formula C10H15BO2S. This compound features a thiophene-substituted dioxaborolane structure, making it a valuable intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its robust stability and reactivity under mild conditions make it ideal for constructing complex heterocyclic frameworks. The product is supplied as a crystalline solid with ??95% purity (HPLC), ensuring consistent performance in research and industrial applications. Proper storage under inert conditions (argon or nitrogen) is recommended to maintain its integrity.

  • CAS No: 193978-23-3
  • Molecular Formula: C10H15BO2S
  • Molecular Weight: 210.11
  • Exact Mass: 210.0885811
  • Monoisotopic Mass: 210.0885811
  • IUPAC Name: 4,4,5,5-tetramethyl-2-thiophen-2-yl-1,3,2-dioxaborolane
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC=CS2
  • Synonyms: 193978-23-3, 4,4,5,5-tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane, DTXSID40443735, DTXCID40394556, 674-696-5

Application

4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane is widely used as a key reagent in palladium-catalyzed cross-coupling reactions to synthesize thiophene-containing pharmaceuticals and organic electronic materials. Its stability and compatibility with diverse reaction conditions make it a preferred choice for constructing conjugated polymers in OLED and photovoltaic research. Researchers also employ it in medicinal chemistry to develop novel heterocyclic compounds with potential biological activity.

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