Description

Description

4-(Trifluoromethyl)benzylamine (CAS No. 27407-11-0) is a high-purity aromatic amine compound with the molecular formula C₈H₈F₃N and IUPAC name [4-(trifluoromethyl)phenyl]methanamine. This specialized chemical features a benzylamine core substituted with a trifluoromethyl group at the para position, offering unique electronic and steric properties for advanced synthetic applications. Our product is rigorously tested to ensure ??98% purity (GC) and is supplied as a clear, colorless to pale yellow liquid with a characteristic amine odor. Suitable for use as a versatile building block in pharmaceutical intermediates, agrochemicals, and materials science research. Packaged under inert gas to ensure stability and shipped with comprehensive analytical data (GC/MS, NMR, HPLC).

Key Attributes:

• High reactivity for nucleophilic substitution and reductive amination
• Trifluoromethyl group enhances lipophilicity and metabolic stability
• Compatible with peptide coupling reagents
• Stored at 2-8??C in tightly sealed containers

Application

4-(Trifluoromethyl)benzylamine serves as a critical intermediate in the synthesis of bioactive molecules, particularly in pharmaceutical research where the CF₃ group improves compound bioavailability. It’s widely employed in the development of kinase inhibitors, GPCR modulators, and PET radiotracer precursors. The compound also finds use in material science for creating fluorinated polyamides and liquid crystal intermediates. Its electron-withdrawing properties make it valuable for constructing electron-deficient aromatic systems in organic electronics.

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