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Atomfair 4-(Trifluoromethyl)benzohydrazide C8H7F3N2O

Description 4-(Trifluoromethyl)benzohydrazide (CAS No. 338-76-1) is a high-purity organic compound with the molecular formula C8H7F3N2O . This specialized reagent is widely used in pharmaceutical and agrochemical research due to its trifluoromethyl functional group, which enhances metabolic stability and lipophilicity. The compound is supplied as a white to off-white crystalline powder with a purity of ??95% (HPLC). It is soluble in common organic solvents such as DMSO, methanol, and ethanol but exhibits limited solubility in water. Proper storage conditions (2-8??C in a tightly sealed container under inert atmosphere) are recommended to ensure long-term stability. Ideal for use in nucleophilic addition reactions,…

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Description

Description

4-(Trifluoromethyl)benzohydrazide (CAS No. 338-76-1) is a high-purity organic compound with the molecular formula C8H7F3N2O. This specialized reagent is widely used in pharmaceutical and agrochemical research due to its trifluoromethyl functional group, which enhances metabolic stability and lipophilicity. The compound is supplied as a white to off-white crystalline powder with a purity of ??95% (HPLC). It is soluble in common organic solvents such as DMSO, methanol, and ethanol but exhibits limited solubility in water. Proper storage conditions (2-8??C in a tightly sealed container under inert atmosphere) are recommended to ensure long-term stability. Ideal for use in nucleophilic addition reactions, hydrazone formation, and as a building block in heterocyclic synthesis.

  • CAS No: 338-76-1
  • Molecular Formula: C8H7F3N2O
  • Molecular Weight: 204.15
  • Exact Mass: 204.05104734
  • Monoisotopic Mass: 204.05104734
  • IUPAC Name: 4-(trifluoromethyl)benzohydrazide
  • SMILES: C1=CC(=CC=C1C(=O)NN)C(F)(F)F
  • Synonyms: 4-(Trifluoromethyl)benzohydrazide, BENZOIC ACID, 4-(TRIFLUOROMETHYL)-, HYDRAZIDE, 608-934-6, 4-(Trifluoromethyl)benzhydrazide, 339-59-3

Application

4-(Trifluoromethyl)benzohydrazide serves as a key intermediate in the synthesis of biologically active molecules, particularly in the development of antifungal and antibacterial agents. Its trifluoromethyl group contributes to enhanced binding affinity in drug-receptor interactions. Researchers utilize this compound in the preparation of hydrazone derivatives for medicinal chemistry applications. It is also employed in material science for the design of advanced fluorinated polymers.

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