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Atomfair 4-nitrophenyl-beta-D-mannopyranoside pNP-beta-D-mannopyranoside C12H15NO8

Description 4-Nitrophenyl-beta-D-mannopyranoside (CAS No. 403-21-4) is a high-purity synthetic glycoside derivative widely used in biochemical and enzymatic research. With the molecular formula C12H15NO8, this compound is specifically designed for studying glycosidase activity, particularly beta-mannosidases. The IUPAC name, (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol, reflects its stereospecific configuration, ensuring optimal performance in enzymatic assays. This substrate yields a chromogenic 4-nitrophenolate ion upon enzymatic cleavage, enabling precise spectrophotometric quantification at 405 nm. Packaged under inert conditions to ensure stability, our product is ideal for kinetic studies, inhibitor screening, and enzyme characterization in both academic and industrial research settings.

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Description

Description

4-Nitrophenyl-beta-D-mannopyranoside (CAS No. 403-21-4) is a high-purity synthetic glycoside derivative widely used in biochemical and enzymatic research. With the molecular formula C12H15NO8, this compound is specifically designed for studying glycosidase activity, particularly beta-mannosidases. The IUPAC name, (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol, reflects its stereospecific configuration, ensuring optimal performance in enzymatic assays. This substrate yields a chromogenic 4-nitrophenolate ion upon enzymatic cleavage, enabling precise spectrophotometric quantification at 405 nm. Packaged under inert conditions to ensure stability, our product is ideal for kinetic studies, inhibitor screening, and enzyme characterization in both academic and industrial research settings.

  • CAS No: 403-21-4
  • Molecular Formula: C12H15NO8
  • Molecular Weight: 301.25
  • Exact Mass: 301.07976644
  • Monoisotopic Mass: 301.07976644
  • IUPAC Name: (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol
  • SMILES: C1=CC(=CC=C1[N+](=O)[O-])O[C@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
  • Synonyms: 35599-02-1, 4-Nitrophenyl-beta-D-mannopyranoside, 4-Nitrophenyl beta-D-mannopyranoside, p-Nitrophenyl beta-D-mannopyranoside, EINECS 252-633-9

Application

4-Nitrophenyl-beta-D-mannopyranoside serves as a critical substrate for detecting and quantifying beta-mannosidase activity in various biological samples. Researchers utilize this compound in high-throughput screening assays to identify potential enzyme inhibitors or activators. Its chromogenic properties make it invaluable for kinetic studies and enzyme mechanism elucidation. The compound is also employed in diagnostic applications to assess lysosomal storage disorders linked to beta-mannosidase deficiencies.

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