Description

Description

4-Fluoro-2-(trifluoromethyl)aniline (CAS No. 393-39-5) is a high-purity fluorinated aromatic amine with the molecular formula C₇H₅F₄N. This compound, also known by its IUPAC name 4-fluoro-2-(trifluoromethyl)aniline, is a versatile building block in organic synthesis and pharmaceutical research. Its unique structure, featuring both fluorine and trifluoromethyl substituents, enhances electron-withdrawing properties, making it valuable for designing advanced materials and bioactive molecules.

Our product is rigorously tested to ensure ??98% purity (GC) and is supplied as a clear to pale yellow liquid. It is packaged under inert gas to maintain stability and is ideal for use in nucleophilic substitutions, cross-coupling reactions, and as a precursor for agrochemicals or pharmaceuticals. Store in a cool, dry place away from light and oxidizing agents.

Synonyms: 2-Amino-5-fluorobenzotrifluoride, Benzenamine, 4-fluoro-2-(trifluoromethyl)-, alpha,alpha,alpha,4-Tetrafluoro-o-toluidine

Application

4-Fluoro-2-(trifluoromethyl)aniline is widely used as an intermediate in the synthesis of fluorinated pharmaceuticals, agrochemicals, and liquid crystals. Its electron-deficient aromatic ring facilitates reactions such as Buchwald-Hartwig amination or Suzuki-Miyaura coupling. Researchers employ it to develop kinase inhibitors, herbicides, and OLED materials due to its enhanced lipophilicity and metabolic stability. Handle with standard aryl amine precautions under fume hoods.

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